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There are 6 purchasable compounds for target: ACSVL5

Wt: 470.6
BDBM50387679
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Wt: 409.5
BDBM50387680
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Wt: 370.4
BDBM50433154
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Wt: 320.3
BDBM50433155
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Wt: 348.4
BDBM50433156
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Wt: 374.4
BDBM50433157
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50387679,50387680,50433154,50433155,50433156,50433157   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50387679
PNG
(CHEMBL2058075)
Show SMILES CCOC(=O)c1ccc(NC(=O)CSc2nnc(CSCc3ccccc3)n2CC)cc1
Show InChI InChI=1S/C23H26N4O3S2/c1-3-27-20(15-31-14-17-8-6-5-7-9-17)25-26-23(27)32-16-21(28)24-19-12-10-18(11-13-19)22(29)30-4-2/h5-13H,3-4,14-16H2,1-2H3,(H,24,28)
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n/an/a 7.60E+3n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate


Citation and Details
More data for this
Ligand-Target Pair
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50387680
PNG
(CHEMBL2058074)
Show SMILES COc1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC=C)cc1
Show InChI InChI=1S/C21H23N5O2S/c1-3-13-26-19(14-22-16-7-5-4-6-8-16)24-25-21(26)29-15-20(27)23-17-9-11-18(28-2)12-10-17/h3-12,22H,1,13-15H2,2H3,(H,23,27)
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n/an/a 6.60E+3n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate


Citation and Details
More data for this
Ligand-Target Pair
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50433157
PNG
(CHEMBL2377766)
Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2nc3CCCCc3s2)CC1
Show InChI InChI=1S/C19H23FN4OS/c20-14-5-7-15(8-6-14)24-11-9-23(10-12-24)13-18(25)22-19-21-16-3-1-2-4-17(16)26-19/h5-8H,1-4,9-13H2,(H,21,22,25)
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n/an/a 77n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis


Citation and Details
More data for this
Ligand-Target Pair
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50433155
PNG
(CHEMBL1711675)
Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2nccs2)CC1
Show InChI InChI=1S/C15H17FN4OS/c16-12-1-3-13(4-2-12)20-8-6-19(7-9-20)11-14(21)18-15-17-5-10-22-15/h1-5,10H,6-9,11H2,(H,17,18,21)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis


Citation and Details
More data for this
Ligand-Target Pair
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50433156
PNG
(CHEMBL2377767)
Show SMILES Cc1nc(NC(=O)CN2CCN(CC2)c2ccc(F)cc2)sc1C
Show InChI InChI=1S/C17H21FN4OS/c1-12-13(2)24-17(19-12)20-16(23)11-21-7-9-22(10-8-21)15-5-3-14(18)4-6-15/h3-6H,7-11H2,1-2H3,(H,19,20,23)
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PC cid
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n/an/a 430n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis


Citation and Details
More data for this
Ligand-Target Pair
Long-chain fatty acid transport protein 1


(Homo sapiens)
BDBM50433154
PNG
(CHEMBL2377765)
Show SMILES Fc1ccc(cc1)N1CCN(CC(=O)Nc2nc3ccccc3s2)CC1
Show InChI InChI=1S/C19H19FN4OS/c20-14-5-7-15(8-6-14)24-11-9-23(10-12-24)13-18(25)22-19-21-16-3-1-2-4-17(16)26-19/h1-8H,9-13H2,(H,21,22,25)
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PC cid
PC sid
UniChem
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PubMed
n/an/a 490n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FLAG-tagged FATP1-mediated [1-14C] oleic acid conversion to [1-14C] oleoyl-CoA after 20 mins by scintillation counting analysis


Citation and Details
More data for this
Ligand-Target Pair