Compounds in cluster

There are 20 purchasable compounds for target: ATAD2

Wt: 423.8 BDBM50365463 Purchase	Wt: 415.4 BDBM50380682 Purchase	Wt: 191.2 BDBM50030938 Purchase	Wt: 236.2 BDBM50030942 Purchase	Wt: 223.2 BDBM50030951 Purchase
Wt: 250.3 BDBM50030935 Purchase	Wt: 238.3 BDBM50030936 Purchase	Wt: 211.2 BDBM50030937 Purchase	Wt: 160.1 BDBM50030939 Purchase	Wt: 190.2 BDBM50030940 Purchase
Wt: 216.2 BDBM50030941 Purchase	Wt: 243.2 BDBM50030958 Purchase	Wt: 238.2 BDBM50030959 Purchase	Wt: 236.3 BDBM50030967 Purchase	Wt: 434.9 BDBM50028142 Purchase

Displayed 1 to 15 (of 20 total ) | Next | Last >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50365463,50380682,50030938,50030942,50030951,50030935,50030936,50030937,50030939,50030940,50030941,50030958,50030959,50030967,50028142
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50028142 (CHEMBL2177300) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	<3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human ATAD2 by BROMOscan assay				J Med Chem 57: 8111-31 (2014) Article DOI: 10.1021/jm5010539 BindingDB Entry DOI: 10.7270/Q23R0VGR
GlaxoSmithKline R&D Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50380682 (CHEMBL2017291 \| I-BET151 (16)) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated ATAD2A (981 to 1108 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030936 (CHEMBL3356578) Show SMILES CC(C)(C)c1csc(NC(=O)C2CCC2)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030937 (CHEMBL3356579) Show SMILES CC1(C)CNC(=O)c2sc(N)nc2C1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030938 (CHEMBL2335381) Show SMILES Cc1cc2n(C)c(=O)n(C)c2cc1N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030939 (CHEMBL3356571) Show SMILES Cc1cc2ncccc2nc1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030940 (CHEMBL3356572) Show SMILES CCN1C(=O)CCc2cc(N)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030941 (CHEMBL3356573) Show SMILES Nc1ccc2CCCN(C(=O)C3CC3)c2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030942 (CHEMBL3356574) Show SMILES Nc1cccc(c1)-c1n[nH]c(n1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030951 (CHEMBL389723) Show SMILES c1ccc(cc1)-c1nnc(o1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030958 (CHEMBL3356575) Show SMILES Nc1cccc(c1)-c1nnc(o1)-c1cccs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030959 (CHEMBL3356576) Show SMILES Nc1ccccc1-c1nnc(o1)-c1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030967 (CHEMBL1338624) Show SMILES NC1=NC2=C(CCCC2)C2(CCCCC2)S1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030942 (CHEMBL3356574) Show SMILES Nc1cccc(c1)-c1n[nH]c(n1)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.50E+5	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to ATAD2 (unknown origin) by protein-observe NMR spectroscopy				Bioorg Med Chem Lett 25: 2461-8 (2015) Article DOI: 10.1016/j.bmcl.2015.04.089 BindingDB Entry DOI: 10.7270/Q2SF2XVC
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50365463 (CHEMBL1232461) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to biotinylated ATAD2A (981 to 1108 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells by bio-layer interferometr...				J Med Chem 58: 4927-39 (2015) Article DOI: 10.1021/acs.jmedchem.5b00613 BindingDB Entry DOI: 10.7270/Q2XD13FK
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens)	BDBM50030935 (CHEMBL3356577) Show SMILES COc1ccc2nc(NC(=O)C(C)C)sc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human ATAD2 (979 to 1108 aa) expressed in Escherichia coli BL21 (DE3) by SOFAST-HMQC NMR spectroscopy				J Med Chem 57: 9687-92 (2014) Article DOI: 10.1021/jm501035j BindingDB Entry DOI: 10.7270/Q29Z96G7
Vanderbilt University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair