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There are 8 purchasable compounds for target: Acid-sensitive potassium channel protein TASK-3

Wt: 317.3
BDBM58520
Purchase
Wt: 360.4
BDBM50312105
Purchase
Wt: 468.5
BDBM50426570
Purchase
Wt: 372.4
BDBM50050445
Purchase
Wt: 306.3
BDBM50050447
Purchase
Wt: 322.3
BDBM50050451
Purchase
Wt: 317.3
BDBM50050457
Purchase
Wt: 344.4
BDBM50050495
Purchase
Wt: 386.4
BDBM50050497
Purchase
Wt: 376.4
BDBM50050540
Purchase
Wt: 360.4
BDBM50050543
Purchase
Wt: 316.3
BDBM50050433
Purchase
Wt: 334.3
BDBM50050437
Purchase
Wt: 330.3
BDBM50050157
Purchase
Wt: 334.3
BDBM50050438
Purchase
Displayed 1 to 15 (of 16 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 58520,50312105,50426570,50050445,50050447,50050451,50050457,50050495,50050497,50050540,50050543,50050433,50050437,50050157,50050438   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50426570
PNG
(CHEMBL2324344)
Show SMILES CCCC(=O)C1CCN(CC1)c1ncnc2CCN(Cc12)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C29H32N4O2/c1-2-6-27(34)23-13-16-32(17-14-23)28-25-19-33(18-15-26(25)30-20-31-28)29(35)24-11-9-22(10-12-24)21-7-4-3-5-8-21/h3-5,7-12,20,23H,2,6,13-19H2,1H3
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n/an/a 35n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin)


J Med Chem 56: 593-624 (2013)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050543
PNG
(CHEMBL1480257)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-8-3-4-11-18(15)21(25)23-16-9-7-10-17(14-16)24-22(26)19-12-5-6-13-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 2.20E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050433
PNG
(CHEMBL3186489)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C20H16N2O2/c23-19(15-8-3-1-4-9-15)21-17-12-7-13-18(14-17)22-20(24)16-10-5-2-6-11-16/h1-14H,(H,21,23)(H,22,24)
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n/an/a 2.30E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050437
PNG
(CHEMBL1532914)
Show SMILES Fc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C20H15FN2O2/c21-16-9-4-8-15(12-16)20(25)23-18-11-5-10-17(13-18)22-19(24)14-6-2-1-3-7-14/h1-13H,(H,22,24)(H,23,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050438
PNG
(CHEMBL3184075)
Show SMILES Fc1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C20H15FN2O2/c21-16-11-9-15(10-12-16)20(25)23-18-8-4-7-17(13-18)22-19(24)14-5-2-1-3-6-14/h1-13H,(H,22,24)(H,23,25)
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n/an/a 2.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050445
PNG
(CHEMBL3317850)
Show SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C24H24N2O2/c1-24(2,3)19-14-12-18(13-15-19)23(28)26-21-11-7-10-20(16-21)25-22(27)17-8-5-4-6-9-17/h4-16H,1-3H3,(H,25,27)(H,26,28)
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n/an/a 3.20E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050447
PNG
(CHEMBL1716797)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccco1
Show InChI InChI=1S/C18H14N2O3/c21-17(13-6-2-1-3-7-13)19-14-8-4-9-15(12-14)20-18(22)16-10-5-11-23-16/h1-12H,(H,19,21)(H,20,22)
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n/an/a 5.90E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050451
PNG
(CHEMBL3182777)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1cccs1
Show InChI InChI=1S/C18H14N2O2S/c21-17(13-6-2-1-3-7-13)19-14-8-4-9-15(12-14)20-18(22)16-10-5-11-23-16/h1-12H,(H,19,21)(H,20,22)
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n/an/a 970n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM58520
PNG
(MLS001035529 | N-(3-benzamidophenyl)-3-pyridinecar...)
Show SMILES O=C(Nc1cccc(NC(=O)c2cccnc2)c1)c1ccccc1
Show InChI InChI=1S/C19H15N3O2/c23-18(14-6-2-1-3-7-14)21-16-9-4-10-17(12-16)22-19(24)15-8-5-11-20-13-15/h1-13H,(H,21,23)(H,22,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050457
PNG
(CHEMBL3188245)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccncc2)c1)c1ccccc1
Show InChI InChI=1S/C19H15N3O2/c23-18(14-5-2-1-3-6-14)21-16-7-4-8-17(13-16)22-19(24)15-9-11-20-12-10-15/h1-13H,(H,21,23)(H,22,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050495
PNG
(CHEMBL3185736)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O2/c1-15-6-3-8-17(12-15)21(25)23-19-10-5-11-20(14-19)24-22(26)18-9-4-7-16(2)13-18/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 150n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050497
PNG
(CHEMBL3181946)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1
Show InChI InChI=1S/C25H26N2O2/c1-17-7-5-8-19(15-17)24(29)27-22-10-6-9-21(16-22)26-23(28)18-11-13-20(14-12-18)25(2,3)4/h5-16H,1-4H3,(H,26,28)(H,27,29)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50312105
PNG
(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 390n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050157
PNG
(CHEMBL1310568)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C21H18N2O2/c1-15-7-5-10-17(13-15)21(25)23-19-12-6-11-18(14-19)22-20(24)16-8-3-2-4-9-16/h2-14H,1H3,(H,22,24)(H,23,25)
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n/an/a 690n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50312105
PNG
(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 990n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050540
PNG
(CHEMBL3182359)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1
Show InChI InChI=1S/C22H20N2O4/c1-27-19-12-5-3-10-17(19)21(25)23-15-8-7-9-16(14-15)24-22(26)18-11-4-6-13-20(18)28-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 710n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050540
PNG
(CHEMBL3182359)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1
Show InChI InChI=1S/C22H20N2O4/c1-27-19-12-5-3-10-17(19)21(25)23-15-8-7-9-16(14-15)24-22(26)18-11-4-6-13-20(18)28-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 1.88E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050157
PNG
(CHEMBL1310568)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1
Show InChI InChI=1S/C21H18N2O2/c1-15-7-5-10-17(13-15)21(25)23-19-12-6-11-18(14-19)22-20(24)16-8-3-2-4-9-16/h2-14H,1H3,(H,22,24)(H,23,25)
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n/an/a 500n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair