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There are 8 purchasable compounds for target: Acid-sensitive potassium channel protein TASK-3

Wt: 317.3
BDBM58520
Wt: 360.4
BDBM50312105
Wt: 306.3
BDBM50050447
Wt: 317.3
BDBM50050457
Wt: 344.4
BDBM50050495
Wt: 386.4
BDBM50050497
Wt: 360.4
BDBM50050543
Wt: 316.3
BDBM50050433

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 58520,50312105,50050447,50050457,50050495,50050497,50050543,50050433   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050433
PNG
(CHEMBL3186489)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C20H16N2O2/c23-19(15-8-3-1-4-9-15)21-17-12-7-13-18(14-17)22-20(24)16-10-5-2-6-11-16/h1-14H,(H,21,23)(H,22,24)
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n/an/a 2.30E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050447
PNG
(CHEMBL1716797)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccco1
Show InChI InChI=1S/C18H14N2O3/c21-17(13-6-2-1-3-7-13)19-14-8-4-9-15(12-14)20-18(22)16-10-5-11-23-16/h1-12H,(H,19,21)(H,20,22)
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n/an/a 5.90E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM58520
PNG
(MLS001035529 | N-(3-benzamidophenyl)-3-pyridinecar...)
Show SMILES O=C(Nc1cccc(NC(=O)c2cccnc2)c1)c1ccccc1
Show InChI InChI=1S/C19H15N3O2/c23-18(14-6-2-1-3-7-14)21-16-9-4-10-17(12-16)22-19(24)15-8-5-11-20-13-15/h1-13H,(H,21,23)(H,22,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050457
PNG
(CHEMBL3188245)
Show SMILES O=C(Nc1cccc(NC(=O)c2ccncc2)c1)c1ccccc1
Show InChI InChI=1S/C19H15N3O2/c23-18(14-5-2-1-3-6-14)21-16-7-4-8-17(13-16)22-19(24)15-9-11-20-12-10-15/h1-13H,(H,21,23)(H,22,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050543
PNG
(CHEMBL1480257)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-8-3-4-11-18(15)21(25)23-16-9-7-10-17(14-16)24-22(26)19-12-5-6-13-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050497
PNG
(CHEMBL3181946)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1
Show InChI InChI=1S/C25H26N2O2/c1-17-7-5-8-19(15-17)24(29)27-22-10-6-9-21(16-22)26-23(28)18-11-13-20(14-12-18)25(2,3)4/h5-16H,1-4H3,(H,26,28)(H,27,29)
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n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50312105
PNG
(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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PC cid
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Article
PubMed
n/an/a 390n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50312105
PNG
(2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide...)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
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PC cid
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PubMed
n/an/a 990n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assay


Citation and Details
More data for this
Ligand-Target Pair
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050495
PNG
(CHEMBL3185736)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Show InChI InChI=1S/C22H20N2O2/c1-15-6-3-8-17(12-15)21(25)23-19-10-5-11-20(14-19)24-22(26)18-9-4-7-16(2)13-18/h3-14H,1-2H3,(H,23,25)(H,24,26)
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PubMed
n/an/a 150n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Citation and Details
More data for this
Ligand-Target Pair