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There are 7 purchasable compounds for target: ABH3

Wt: 338.7
BDBM50447913
Wt: 338.7
BDBM50447914
Wt: 245.3
BDBM50447922
Wt: 360.4
BDBM50447931
Wt: 228.2
BDBM50447932
Wt: 214.2
BDBM50447934
Wt: 338.7
BDBM50447956

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50447913,50447914,50447922,50447931,50447932,50447934,50447956   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447913
PNG
(CHEMBL3114994)
Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(Cl)cc1
Show InChI InChI=1S/C18H15ClN4O/c1-11-14(10-12-6-8-13(19)9-7-12)17(24)23(22-11)18-20-15-4-2-3-5-16(15)21-18/h2-9,22H,10H2,1H3,(H,20,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447914
PNG
(CHEMBL3114992)
Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccccc1Cl
Show InChI InChI=1S/C18H15ClN4O/c1-11-13(10-12-6-2-3-7-14(12)19)17(24)23(22-11)18-20-15-8-4-5-9-16(15)21-18/h2-9,22H,10H2,1H3,(H,20,21)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447922
PNG
(CHEMBL3114975)
Show SMILES Cc1[nH]n(-c2nc3ccccc3s2)c(=O)c1C
Show InChI InChI=1S/C12H11N3OS/c1-7-8(2)14-15(11(7)16)12-13-9-5-3-4-6-10(9)17-12/h3-6,14H,1-2H3
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PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447956
PNG
(CHEMBL3114993)
Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1cccc(Cl)c1
Show InChI InChI=1S/C18H15ClN4O/c1-11-14(10-12-5-4-6-13(19)9-12)17(24)23(22-11)18-20-15-7-2-3-8-16(15)21-18/h2-9,22H,10H2,1H3,(H,20,21)
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n/an/a 540n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447932
PNG
(CHEMBL3114973)
Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1C
Show InChI InChI=1S/C12H12N4O/c1-7-8(2)15-16(11(7)17)12-13-9-5-3-4-6-10(9)14-12/h3-6,15H,1-2H3,(H,13,14)
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PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447934
PNG
(CHEMBL3114982)
Show SMILES Cc1cc(=O)n([nH]1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C11H10N4O/c1-7-6-10(16)15(14-7)11-12-8-4-2-3-5-9(8)13-11/h2-6,14H,1H3,(H,12,13)
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n/an/a 3.60E+3n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3


(Homo sapiens)
BDBM50447931
PNG
(CHEMBL3115001)
Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C22H24N4O/c1-14-17(13-15-9-11-16(12-10-15)22(2,3)4)20(27)26(25-14)21-23-18-7-5-6-8-19(18)24-21/h5-12,25H,13H2,1-4H3,(H,23,24)
PDB
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PC cid
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Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Hyogo University of Health Science

Curated by ChEMBL


Assay Description
Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis


Citation and Details
More data for this
Ligand-Target Pair