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There are 1 purchasable compounds for target: Adipose triglyceride lipase

Wt: 281.3
BDBM50084672
Wt: 281.3
BDBM50084690
Wt: 355.4
BDBM50084766
Wt: 311.3
BDBM50084919
Wt: 355.4
BDBM50084767
Wt: 334.2
BDBM50084770
Wt: 279.3
BDBM50084843
Wt: 308.4
BDBM50084844
Wt: 341.4
BDBM50084928
Wt: 315.4
BDBM50084915
Wt: 297.3
BDBM50084653
Wt: 311.3
BDBM50084662
Wt: 281.3
BDBM50084668
Wt: 297.3
BDBM50084691
Wt: 357.4
BDBM50084765

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50084672,50084690,50084766,50084919,50084767,50084770,50084843,50084844,50084928,50084915,50084653,50084662,50084668,50084691,50084765   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084653
PNG
(CHEMBL2094513 | DNDI1417188)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1O
Show InChI InChI=1S/C17H19N3O2/c21-16-7-6-14(12-17(16)22)13-18-20-10-8-19(9-11-20)15-4-2-1-3-5-15/h1-7,12-13,21-22H,8-11H2/b18-13+
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n/an/a 1.10E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084928
PNG
(CHEMBL3427365)
Show SMILES COc1ccc(NC(=O)N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C19H23N3O3/c1-24-17-9-8-15(14-18(17)25-2)20-19(23)22-12-10-21(11-13-22)16-6-4-3-5-7-16/h3-9,14H,10-13H2,1-2H3,(H,20,23)
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n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084668
PNG
(CHEMBL3427322)
Show SMILES Oc1cccc(\C=N\N2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C17H19N3O/c21-17-8-4-5-15(13-17)14-18-20-11-9-19(10-12-20)16-6-2-1-3-7-16/h1-8,13-14,21H,9-12H2/b18-14+
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n/an/a 7.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084672
PNG
(CHEMBL3427323)
Show SMILES Oc1ccccc1\C=N\N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C17H19N3O/c21-17-9-5-4-6-15(17)14-18-20-12-10-19(11-13-20)16-7-2-1-3-8-16/h1-9,14,21H,10-13H2/b18-14+
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n/an/a 7.50E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084690
PNG
(CHEMBL3427324)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C17H19N3O/c21-17-8-6-15(7-9-17)14-18-20-12-10-19(11-13-20)16-4-2-1-3-5-16/h1-9,14,21H,10-13H2/b18-14+
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n/an/a 5.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084691
PNG
(CHEMBL3427325)
Show SMILES Oc1ccc(\C=N\N2CCN(CC2)c2ccccc2)c(O)c1
Show InChI InChI=1S/C17H19N3O2/c21-16-7-6-14(17(22)12-16)13-18-20-10-8-19(9-11-20)15-4-2-1-3-5-15/h1-7,12-13,21-22H,8-11H2/b18-13+
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n/an/a 1.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084765
PNG
(CHEMBL3427327)
Show SMILES C1CN(CCN1\N=C\c1cccc(Oc2ccccc2)c1)c1ccccc1
Show InChI InChI=1S/C23H23N3O/c1-3-9-21(10-4-1)25-14-16-26(17-15-25)24-19-20-8-7-13-23(18-20)27-22-11-5-2-6-12-22/h1-13,18-19H,14-17H2/b24-19+
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n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084766
PNG
(CHEMBL3427328)
Show SMILES COc1cc(OC)c(\C=N\N2CCN(CC2)c2ccccc2)cc1OC
Show InChI InChI=1S/C20H25N3O3/c1-24-18-14-20(26-3)19(25-2)13-16(18)15-21-23-11-9-22(10-12-23)17-7-5-4-6-8-17/h4-8,13-15H,9-12H2,1-3H3/b21-15+
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n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084767
PNG
(CHEMBL3427329)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)cc(OC)c1OC
Show InChI InChI=1S/C20H25N3O3/c1-24-18-13-16(14-19(25-2)20(18)26-3)15-21-23-11-9-22(10-12-23)17-7-5-4-6-8-17/h4-8,13-15H,9-12H2,1-3H3/b21-15+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084770
PNG
(CHEMBL3427331)
Show SMILES Clc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1Cl
Show InChI InChI=1S/C17H17Cl2N3/c18-16-7-6-14(12-17(16)19)13-20-22-10-8-21(9-11-22)15-4-2-1-3-5-15/h1-7,12-13H,8-11H2/b20-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084843
PNG
(CHEMBL3211065)
Show SMILES Cc1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C18H21N3/c1-16-7-9-17(10-8-16)15-19-21-13-11-20(12-14-21)18-5-3-2-4-6-18/h2-10,15H,11-14H2,1H3/b19-15+
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n/an/a>2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084844
PNG
(CHEMBL3427337)
Show SMILES CN(C)c1ccc(\C=N\N2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C19H24N4/c1-21(2)18-10-8-17(9-11-18)16-20-23-14-12-22(13-15-23)19-6-4-3-5-7-19/h3-11,16H,12-15H2,1-2H3/b20-16+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084915
PNG
(CHEMBL3427352)
Show SMILES C1CN(CCN1\N=C\c1cccc2ccccc12)c1ccccc1
Show InChI InChI=1S/C21H21N3/c1-2-10-20(11-3-1)23-13-15-24(16-14-23)22-17-19-9-6-8-18-7-4-5-12-21(18)19/h1-12,17H,13-16H2/b22-17+
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n/an/a 2.00E+5n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084919
PNG
(CHEMBL3427356)
Show SMILES Oc1ccc(\C=N\N2CCN(Cc3ccccc3)CC2)c(O)c1
Show InChI InChI=1S/C18H21N3O2/c22-17-7-6-16(18(23)12-17)13-19-21-10-8-20(9-11-21)14-15-4-2-1-3-5-15/h1-7,12-13,22-23H,8-11,14H2/b19-13+
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Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair
Patatin-like phospholipase domain-containing protein 2


(Mus musculus)
BDBM50084662
PNG
(CHEMBL3427321)
Show SMILES COc1cc(\C=N\N2CCN(CC2)c2ccccc2)ccc1O
Show InChI InChI=1S/C18H21N3O2/c1-23-18-13-15(7-8-17(18)22)14-19-21-11-9-20(10-12-21)16-5-3-2-4-6-16/h2-8,13-14,22H,9-12H2,1H3/b19-14+
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n/an/a 6.00E+4n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant ATGL expressed in African green monkey COS7 cells assessed as reduction in triglyceride hydrolase activity using radi...


Citation and Details
More data for this
Ligand-Target Pair