Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hits in this display   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

LigandBDBM13738(5-methyl-5-(propan-2-yl)-2-{[2-(trifluoromethyl)ph...)Copy SMILESCopy InChI

Affinity DataKi:  503nM ΔG°:  -35.6kJ/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI