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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Amgen
Ligand
BDBM13738
(5-methyl-5-(propan-2-yl)-2-{[2-(trifluoromethyl)ph...)
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Affinity Data
Ki: 503nM ΔG°: -35.6kJ/mole
pH: 7.2 T: 2°C
Assay Description:
Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...
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