SMILES String Search

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 60 hits in this display

Muscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Arizona

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 25nMMore data for this Ligand-Target Pair

PDB Reactome pathway
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Acetylcholinesterase(Mus musculus (mouse))
Mayo Clinic

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 460nM ΔG°: -36.2kJ/molepH: 7.0 T: 2°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair

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3D Structure (crystal)

Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 460nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 962nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 1.30E+3nMMore data for this Ligand-Target Pair

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Nicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 3.13E+3nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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Acetylcholinesterase(Mus musculus (mouse))
Mayo Clinic

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 3.50E+3nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair

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3D Structure (crystal)

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 5.73E+3nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair

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Nicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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Nicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
GoogleScholar

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Sigma non-opioid intracellular receptor 1(RAT)
TBA

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

PDB
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Sigma non-opioid intracellular receptor 1(RAT)
TBA

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

PDB
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Nicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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Nicotinic acetylcholine receptor(RAT)
R. J. Reynolds Tobacco

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
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Uncharacterized protein(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

PDB
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Uncharacterized protein(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

PDB
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Cholinergic receptor nicotinic alpha 6 subunit(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
GoogleScholar

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Cholinergic receptor nicotinic alpha 6 subunit(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/TrEMBL
GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-6(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/SwissProt
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Neuronal acetylcholine receptor subunit alpha-6(Chick)
University Of Milan

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

UniProtKB/SwissProt
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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
Georgetown University

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

PDB Reactome pathway
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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath

Curated by PDSP K_i Database

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+4nMMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: 2.17E+4nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: >1.00E+5nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Ki: >1.00E+5nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair

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Acetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

Ki: 6.00E+6nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair

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3D Structure (crystal)

Acetylcholinesterase(Torpedo marmorata (Marbled electric ray))
UniversitÉ

PNG

BDBM50060533(1,12-Bis(trimethyl ammonium)dodecane dibromide | 1...)

IC50: 93.2nMpH: 4.0 T: 2°CAssay Description:The inhibitory activity of the equilibrated mixtures was determined. The activity of AChE was monitored by following the linear change in absorbance...More data for this Ligand-Target Pair

PDB MMDB
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Histamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

IC50: 820nMAssay Description:Inhibition of histone H3 receptorMore data for this Ligand-Target Pair

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Acetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

IC50: 1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Acetylcholinesterase(Torpedo marmorata (Marbled electric ray))
UniversitÉ

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

IC50: 1.06E+3nMpH: 4.0 T: 2°CAssay Description:The inhibitory activity of the equilibrated mixtures was determined. The activity of AChE was monitored by following the linear change in absorbance...More data for this Ligand-Target Pair

PDB MMDB
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3D Structure (crystal)

Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50147563(CHEMBL109458 | Trimethyl-octadecyl-ammonium; bromi...)

IC50: 3.15E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 4.37E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50060597(CHEMBL109747 | CHEMBL113150 | CHEMBL325636 | Cetri...)

IC50: 5.79E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Acetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

IC50: 5.90E+3nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair

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3D Structure (crystal)

Co-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 6.50E+3nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...More data for this Ligand-Target Pair

PDB
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60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 7.40E+3nMAssay Description:Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...More data for this Ligand-Target Pair

PDB Reactome pathway
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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50060597(CHEMBL109747 | CHEMBL113150 | CHEMBL325636 | Cetri...)

IC50: 8.15E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50060597(CHEMBL109747 | CHEMBL113150 | CHEMBL325636 | Cetri...)

IC50: 9.68E+3nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Co-chaperonin GroES(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 1.20E+4nMAssay Description:Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50147570(CHEMBL109737 | Dodecyl-dimethyl-amine | N,N-dimeth...)

IC50: 1.48E+4nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50060599(CHEMBL109873 | Dodecyl-trimethyl-ammonium; bromide)

IC50: 1.63E+4nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Ubiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair

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Apoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 2.75E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50147552(CHEMBL112826 | CHEMBL112888 | Dodecyl-dimethyl-amm...)

IC50: 3.00E+4nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Dynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL

PNG

BDBM50147552(CHEMBL112826 | CHEMBL112888 | Dodecyl-dimethyl-amm...)

IC50: 3.38E+4nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair

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Thiosulfate sulfurtransferase(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: >1.00E+5nMAssay Description:Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...More data for this Ligand-Target Pair

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Caspase-9(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair

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Apoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair

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Chaperonin GroEL(Escherichia coli)
Indiana University School Of Medicine

Curated by ChEMBL

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

IC50: 2.10E+5nMAssay Description:Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...More data for this Ligand-Target Pair

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Phospholipase B(Cryptococcus neoformans)
The University Of Sydney

Curated by ChEMBL

PNG

BDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)

IC50: >2.50E+5nMAssay Description:Inhibition of Cryptococccus neoformans H99 PLB1activityMore data for this Ligand-Target Pair

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Phospholipase B(Cryptococcus neoformans)
The University Of Sydney

Curated by ChEMBL

PNG

BDBM50060533(1,12-Bis(trimethyl ammonium)dodecane dibromide | 1...)

IC50: >2.50E+5nMAssay Description:Inhibition of Cryptococccus neoformans H99 PLB1activityMore data for this Ligand-Target Pair

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Acetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
University Of North Carolina

Curated by ChEMBL

PNG

BDBM50055166(CHEMBL136229 | CHEMBL150054 | Hexyl-trimethyl-ammo...)

IC50: 8.16E+5nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair

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Acetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL

PNG

BDBM50055166(CHEMBL136229 | CHEMBL150054 | Hexyl-trimethyl-ammo...)

IC50: 8.17E+5nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair

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PNG

BDBM197287(SAMPL4, OA)
University Of California San Diego

PNG

BDBM50055166(CHEMBL136229 | CHEMBL150054 | Hexyl-trimethyl-ammo...)

Kd: 1.94E+5nMpH: 11.5 T: 2°CAssay Description:The NMR experiments were carried out in 10 mM sodium phosphate buffer at a pH of 11.3, while the ITC experiments were performed in 50 mM sodium phosp...More data for this Ligand-Host Pair

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Acetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
University Of Toledo

Curated by ChEMBL

PNG

BDBM50038416((1,6-trimethyl ammonium)hexane; dibromide | CHEMBL...)

Kd: 1.80E+3nMAssay Description:Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)Checked by AuthorMore data for this Ligand-Target Pair

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Streptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay

PNG

BDBM58941(CHEMBL307346 | Hexadecyltrimethylammonium hydroxid...)

EC50: 1.96E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair

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PNG

BDBM197309(SAMPL5, OAMe | SAMPL5, TEMOA)
University Of California San Diego

PNG

BDBM50055166(CHEMBL136229 | CHEMBL150054 | Hexyl-trimethyl-ammo...)

Kd: 4.33E+4nMpH: 11.5 T: 2°CAssay Description:The NMR experiments were carried out in 10 mM sodium phosphate buffer at a pH of 11.3, while the ITC experiments were performed in 50 mM sodium phosp...More data for this Ligand-Host Pair

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Displayed 1 to 50 (of 60 total ) | Next | Last >>

Filter my 60 hits

Targets 25▿
- Acetylcholinesterase 9
- Dynamin-1 9
- Neuronal acetylcholine receptor subunit alpha-4 7
- Nicotinic acetylcholine receptor 5
- Cholinergic receptor nicotinic alpha 6 subunit 2
- Apoptotic protease-activating factor 1 2
- Neuronal acetylcholine receptor subunit alpha-7 2
- Co-chaperonin GroES 2
- Sigma non-opioid intracellular receptor 1 2
- Neuronal acetylcholine receptor subunit alpha-4/beta-2 2
- Neuronal acetylcholine receptor subunit alpha-6 2
- Phospholipase B 2
- Uncharacterized protein 2
- 60 kDa heat shock protein, mitochondrial 1
- Histamine H3 receptor 1
- Caspase-9 1
- Thiosulfate sulfurtransferase 1
- Neuronal acetylcholine receptor subunit alpha-3 1
- Streptokinase A 1
- BDBM197287 1
- Muscarinic acetylcholine receptor M2 1
- Chaperonin GroEL 1
- BDBM197309 1
- Ubiquitin-conjugating enzyme E2 N 1
- Acetylcholine receptor subunit alpha/beta/delta/gamma 1
Publications 28▿
- Bioorg Med Chem Lett 14: 3275-8 (2004) 9
- Mol Pharmacol 63: 1329-37 (2003) 6
- Bioorg Med Chem Lett 29: 1106-1112 (2019) 5
- Mol Pharmacol 53: 950-62 (1998) 4
- Bioorg Med Chem Lett 12: 3067-71 (2002) 4
- J Comput Aided Mol Des 31: 1-19 (2016) 2
- Mol Pharmacol 54: 322-33 (1998) 2
- Mol Pharmacol 29: 448-54 (1986) 2
- J Med Chem 51: 3154-70 (2008) 2
- Chembiochem 2: 438-44 (2001) 2
- Bioorg Med Chem 16: 2968-73 (2008) 2
- Mol Pharmacol 64: 1283-94 (2003) 2
- J Med Chem 49: 811-6 (2006) 2
- Proc Natl Acad Sci U S A 81: 4983-7 (1984) 2
- J Med Chem 40: 4360-71 (1998) 1
- J Pharmacol Exp Ther 284: 500-7 (1998) 1
- J Pharmacol Exp Ther 276: 289-97 (1996) 1
- PubChem Bioassay (2011) 1
- Biochemistry 52: 7486-99 (2013) 1
- J Med Chem 39: 5064-71 (1997) 1
- PubChem Bioassay (2011) 1
- J Med Chem 37: 4417-20 (1995) 1
- PubChem Bioassay (2009) 1
- Bioorg Med Chem 22: 4474-89 (2014) 1
- J Pharmacol Exp Ther 270: 159-66 (1994) 1
- Mol Pharmacol 48: 280-7 (1995) 1
- PubChem Bioassay (2011) 1
- PubChem Bioassay (2011) 1
Institutions 24▿
- The University Of Newcastle 9
- University Of Milan 6
- Indiana University School Of Medicine 5
- University Of Bath 4
- Burnham Center For Chemical Genomics 4
- University Of Kentucky 4
- Georgetown University 3
- TBA 2
- University Of California San Diego 2
- UniversitÉ 2
- Barrow Neurological Institute 2
- The University Of Sydney 2
- R. J. Reynolds Tobacco 2
- Universit£ 2
- Johnson & Johnson Pharmaceutical Research And Development 2
- University Of North Carolina 1
- Abbott Laboratories 1
- University Of Toledo 1
- Mayo Clinic 1
- University Of California 1
- Harvard University 1
- Broad Institute 1
- University Of Arizona 1
- Institut De Chimie Des Substances Naturelles 1
Affinity: 25 to 6.0E+6 nM▿
- Ki 29
- IC50 27
- Kd 3
- EC50 1
- ΔG 2
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 9