Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50039142(17-Hydroxy-10-hydroxymethyl-13-methyl-1,2,3,4,8,9,...)
Affinity DataKi:  4.50E+4nMAssay Description:The binding affinity was determined on Cytochrome P450 19A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50041411(CHEMBL3356399)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of purified recombinant PTP1B catalytic domain (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50041408(CHEMBL3356400)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of purified recombinant PTP1B catalytic domain (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50039142(17-Hydroxy-10-hydroxymethyl-13-methyl-1,2,3,4,8,9,...)
Affinity DataIC50:  1.40E+5nMAssay Description:In vitro competetitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Jordan

LigandPNGBDBM91716(11alpha-Hydroxyandrost-4-en-3,17-dione, 5)
Affinity DataIC50:  1.41E+5nMAssay Description:AChE and BChE inhibiting activities were measured in vitro by a modified spectrophotometric method previously developed by Ellman et. al.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Sage Therapeutics

US Patent
LigandPNGBDBM521714(US11149056, Compound U6461)
Affinity DataEC50: >1.00E+4nMAssay Description:Cells are transferred as suspension in serum-free medium to the QPatch HTX system and kept in the cell storage tank/stirrer during experiments. All s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNPC1-like intracellular cholesterol transporter 1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50045537(CHEMBL3311218)
Affinity DataEC50:  1.50E+3nMAssay Description:Binding affinity to FLAG/tGFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as localization after 24 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNPC1-like intracellular cholesterol transporter 1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50045552(7-OXOCHOLESTEROL | CHEBI:64294)
Affinity DataEC50:  8.70E+3nMAssay Description:Binding affinity to FLAG/tGFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as localization after 24 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Sage Therapeutics

US Patent
LigandPNGBDBM521714(US11149056, Compound U6461)
Affinity DataEC50: >1.00E+4nMAssay Description:Cells are transferred as suspension in serum-free medium to the QPatch HTX system and kept in the cell storage tank/stirrer during experiments. All s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent