Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 9 hits in this display
BDBM50039142(17-Hydroxy-10-hydroxymethyl-13-methyl-1,2,3,4,8,9,...)
IC50: 3.80E+3nMAssay Description:Inhibition of purified recombinant PTP1B catalytic domain (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
IC50: 5.00E+4nMAssay Description:Inhibition of purified recombinant PTP1B catalytic domain (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
BDBM50039142(17-Hydroxy-10-hydroxymethyl-13-methyl-1,2,3,4,8,9,...)
BDBM91716(11alpha-Hydroxyandrost-4-en-3,17-dione, 5)
IC50: 1.41E+5nMAssay Description:AChE and BChE inhibiting activities were measured in vitro by a modified spectrophotometric method previously developed by Ellman et. al.More data for this Ligand-Target Pair
BDBM521714(US11149056, Compound U6461)
BDBM50045552(7-OXOCHOLESTEROL | CHEBI:64294)
EC50: 8.70E+3nMAssay Description:Binding affinity to FLAG/tGFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as localization after 24 hrs by fluoresce...More data for this Ligand-Target Pair
BDBM521714(US11149056, Compound U6461)
EC50: >1.00E+4nMAssay Description:Cells are transferred as suspension in serum-free medium to the QPatch HTX system and kept in the cell storage tank/stirrer during experiments. All s...More data for this Ligand-Target Pair