Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 122 hits in this display   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  336nMAssay Description:Displacement of 1,8-ANS from aFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270022(O2C(CH2)4CO2 dianion | adipate | adipate dianion |...)
Affinity DataKi:  410nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  670nM ΔG°:  -35.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  690nM ΔG°:  -35.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  802nMAssay Description:Displacement of 1,8-ANS from eFABP by fluorescence based-assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataKi:  1.78E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  3.06E+3nM ΔG°:  -32.0kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataKi:  3.62E+3nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataKi:  4.40E+3nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Affinity DataKi:  5.41E+3nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50240408(1-hexanecarboxylate | CH3-[CH2]5-COO(-) | enanthat...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Affinity DataKi:  8.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Affinity DataKi:  9.12E+3nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50240408(1-hexanecarboxylate | CH3-[CH2]5-COO(-) | enanthat...)
Affinity DataKi:  1.67E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Affinity DataKi:  1.96E+4nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity to GST-tagged PPARG LBD (unknown origin) by Fluormone Pan-PPAR Green tracer based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270010(octanedioate)
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Affinity DataKi:  3.72E+4nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Affinity DataKi:  6.86E+4nM ΔG°:  -23.8kJ/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 11(Homo sapiens (Human))
Kyorin University

Curated by ChEMBL
LigandPNGBDBM23432(octanoate | octanoate, 1 | octanoic acid | octanoi...)
Affinity DataKi:  2.36E+5nMAssay Description:TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270010(octanedioate)
Affinity DataKi:  1.13E+6nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM50270022(O2C(CH2)4CO2 dianion | adipate | adipate dianion |...)
Affinity DataKi:  1.58E+6nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  930nMAssay Description:In vitro inhibitory concentration against adipocyte fatty acid binding protein(A-FABP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, intestinal(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibitory concentration against intestinal fatty acid binding protein(I-FABP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibitory concentration against heart and muscle fatty acid binding protein(H-FABP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
University of T£bingen

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 2(Homo sapiens (Human))
University of T£bingen

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of TLR2 agonist Pam3Cys-Ser-(Lys)4-OH-mediated IL8 secretion in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  5.40E+3nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  7.40E+3nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins by photometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50:  2.40E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50463966(CHEBI:28822 | Elcosanoic Acid)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Medical College Of Wiscosin

LigandPNGBDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Affinity DataIC50:  6.82E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50357391(CHEMBL1917282)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human VHR using pNpp as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDynamin-1(Homo sapiens (Human))
The University Of Newcastle

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required against dynamin-1 GTPase activity of sheep brain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50357391(CHEMBL1917282)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human HePTP using pNpp as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Bos taurus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Bos taurus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242348(CHEMBL460025 | pentadecanoic acid)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Bos taurus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Bos taurus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242348(CHEMBL460025 | pentadecanoic acid)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, intestinal(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKd:  3.72E+3nMAssay Description:Binding affinity against Fatty acid-binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.14E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
Affinity DataEC50:  4.36E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  7.01E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human N-terminal FLAG-tagged GPR84 receptor stably expressed in CHO cells assessed as inhibition of forskolin-induced cAMP produc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human N-terminal FLAG-tagged GPR84 receptor stably expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  2.50E+4nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells assessed as beta-arrestin 2 recruitment by beta-galactosidase based PathHunter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at human Gi1alpha-coupled GPR84 expressed in baculovirus infected Sf9 insect cells assessed as stimulation of [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
Affinity DataEC50:  9.61E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at recombinant human N-terminally HA-tagged GPR84 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of forskolin-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  8.87E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells co-expressing Galpha16/Gqs5/Gqo5/Gqi9 assessed as increase in calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  3.49E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataEC50:  3.50E+4nMAssay Description:Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  7.60E+3nMAssay Description:Partial agonist activity at full length human PPARG expressed in African green monkey COS7 cells assessed as increase in receptor activation incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50556776(CHEBI:29019 | NONANOATE | Nonanoic Acid | Nonanoic...)
Affinity DataEC50:  5.23E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
Affinity DataEC50:  7.70E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  8.80E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50556776(CHEBI:29019 | NONANOATE | Nonanoic Acid | Nonanoic...)
Affinity DataEC50:  7.02E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
Affinity DataEC50:  8.60E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.44E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  6.08E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human N-terminal-FLAG-tagged human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human GPR84 assessed as beta-arrestin recruitment by beta-galactosidase complementation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  7.42E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity against Adipocyte lipid binding proteinMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKd:  8.30E+4nMAssay Description:Binding affinity against Adipocyte lipid binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  759nMAssay Description:Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Affinity DataEC50:  7.94E+3nMAssay Description:Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKd:  802nMAssay Description:Binding affinity to human kFABPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus)
University Of San Francisco

LigandPNGBDBM23434(dodecanoate | dodecanoate, 3)
Affinity DataKd:  900nMpH: 7.0 T: 2°CAssay Description:Ligand binding to A. aeolicus LpxC was assayed by isothermal titration using isothermal microcalorimeter from Microcal, Inc. (Northampton, MA). The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Chongqing Medical University

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  5.40E+4nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus)
University Of San Francisco

LigandPNGBDBM23432(octanoate | octanoate, 1 | octanoic acid | octanoi...)
Affinity DataKd: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Ligand binding to A. aeolicus LpxC was assayed by isothermal titration using isothermal microcalorimeter from Microcal, Inc. (Northampton, MA). The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus)
University Of San Francisco

LigandPNGBDBM23433(decanoate | decanoate, 2)
Affinity DataKd:  7.00E+3nMpH: 7.0 T: 2°CAssay Description:Ligand binding to A. aeolicus LpxC was assayed by isothermal titration using isothermal microcalorimeter from Microcal, Inc. (Northampton, MA). The e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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