Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 122 hits in this display
BDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50270022(O2C(CH2)4CO2 dianion | adipate | adipate dianion |...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Ki: 690nM ΔG°: -35.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Ki: 1.78E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
Ki: 1.93E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
Ki: 2.17E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
Ki: 2.64E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Ki: 3.06E+3nM ΔG°: -32.0kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
BDBM50240408(1-hexanecarboxylate | CH3-[CH2]5-COO(-) | enanthat...)
BDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
BDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
BDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
Ki: >1.00E+4nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50240408(1-hexanecarboxylate | CH3-[CH2]5-COO(-) | enanthat...)
BDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
Ki: 1.96E+4nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
BDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
BDBM23432(octanoate | octanoate, 1 | octanoic acid | octanoi...)
BDBM50270022(O2C(CH2)4CO2 dianion | adipate | adipate dianion |...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
IC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
IC50: 1.02E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
IC50: 1.28E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1...More data for this Ligand-Target Pair
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
BDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
BDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
BDBM50488776(Behenic Acid | CHEBI:28941 | Docosanoic Acid)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50463966(CHEBI:28822 | Elcosanoic Acid)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM16433(CHEMBL14184 | Caproic acid | Hexanoic acid | n-Cap...)
Dynamin-1(Homo sapiens (Human))The University Of Newcastle
Curated by ChEMBL
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50242348(CHEMBL460025 | pentadecanoic acid)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50242348(CHEMBL460025 | pentadecanoic acid)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
EC50: 1.14E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
BDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
BDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
EC50: 4.36E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
EC50: 7.01E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
BDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
EC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
EC50: 9.61E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
BDBM50511038(CHEBI:45919 | Tridecanoate | Tridecanoic Acid | Tr...)
EC50: 1.70E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
EC50: 8.87E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50485608(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)
EC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
BDBM50511009(12-Hydroxy-Dodecanoic Acid | CHEBI:39567 | CHEMBL5...)
EC50: >1.00E+5nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
EC50: 3.49E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50556776(CHEBI:29019 | NONANOATE | Nonanoic Acid | Nonanoic...)
BDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
EC50: 7.70E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
EC50: 8.80E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
BDBM50556776(CHEBI:29019 | NONANOATE | Nonanoic Acid | Nonanoic...)
BDBM50511006(CHEBI:32368 | FEMA NO. 3245 | NSC-7885 | Undecanoa...)
EC50: 8.60E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
EC50: 1.05E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
EC50: 1.44E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50147581(1-tridecanecarboxylic acid | 14:0 | CH3-[CH2]12-CO...)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM50240485(18:0 | C18:0 | CH3-[CH2]16-COOH | CHEMBL46403 | Oc...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
BDBM50180948(CHEBI:30805 | DODECANOATE | Dodecanoic Acid | Dode...)
BDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
BDBM23434(dodecanoate | dodecanoate, 3)
BDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
BDBM23432(octanoate | octanoate, 1 | octanoic acid | octanoi...)
Kd: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:Ligand binding to A. aeolicus LpxC was assayed by isothermal titration using isothermal microcalorimeter from Microcal, Inc. (Northampton, MA). The e...More data for this Ligand-Target Pair
BDBM23433(decanoate | decanoate, 2)
Kd: 7.00E+3nMpH: 7.0 T: 2°CAssay Description:Ligand binding to A. aeolicus LpxC was assayed by isothermal titration using isothermal microcalorimeter from Microcal, Inc. (Northampton, MA). The e...More data for this Ligand-Target Pair
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