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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
Nitric oxide synthase, inducible
(Mus musculus (mouse))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061231
(2-Amino-5-(N'-propyl-guanidino)-pentanoic acid | C...)
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Affinity Data
Ki: 1.80nM
Assay Description:
Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Nitric oxide synthase, brain
(Rattus norvegicus (rat))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061231
(2-Amino-5-(N'-propyl-guanidino)-pentanoic acid | C...)
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Affinity Data
Ki: 57nM
Assay Description:
Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
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PC sid
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Article
PubMed
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Target
Nitric oxide synthase, endothelial
(Bos taurus (bovine))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
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Affinity Data
Ki: 5.90E+3nM
Assay Description:
Compound was tested for binding affinity against Endothelial nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
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PDB
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Article
PubMed
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Target
Nitric oxide synthase, inducible
(Mus musculus (mouse))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061233
(2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid | CH...)
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Affinity Data
Ki: 6.10E+3nM
Assay Description:
Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, endothelial
(Bos taurus (bovine))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061231
(2-Amino-5-(N'-propyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.50E+3nM
Assay Description:
Compound was tested for binding affinity against Endothelial nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, endothelial
(Bos taurus (bovine))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061233
(2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid | CH...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.50E+3nM
Assay Description:
Compound was tested for binding affinity against Endothelial nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, brain
(Rattus norvegicus (rat))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+4nM
Assay Description:
Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Mus musculus (mouse))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40E+4nM
Assay Description:
Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, brain
(Rattus norvegicus (rat))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50061233
(2-Amino-5-(N'-ethyl-guanidino)-pentanoic acid | CH...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+4nM
Assay Description:
Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human))
Christian-Albrechts-University
Ligand
BDBM235688
(hDDAH inhibitor, 2b)
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Affinity Data
Ki: 9.00E+4nM ΔG°: -24.0kJ/mole
pH: 7.4 T: 2°C
Assay Description:
A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
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Affinity Data
IC50: 90nM
Assay Description:
Inhibitory activity against human neuronal nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Inhibitory activity against human endothelial nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 340nM
Assay Description:
Inhibitory activity of compound against human inducible nitiric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 540nM
Assay Description:
In vitro inhibition of endothelial nitric oxide synthase.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 890nM
Assay Description:
Concentration required to inhibit neuronal nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
In vitro inhibition of inducible nitric oxide synthase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Mus musculus (mouse))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.30E+3nM
Assay Description:
Tested for inhibition of mouse inducible nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Rattus norvegicus)
G. D. Searle Research And Development
Curated by
ChEMBL
Ligand
BDBM50030279
(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+4nM
Assay Description:
Tested for inhibition of rat brain inducible nitric oxide synthase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nitric oxide synthase, inducible
(Mus musculus (mouse))
Northwestern University
Curated by
ChEMBL
Ligand
BDBM50441055
(CHEMBL1744478)
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Copy InChI
Affinity Data
IC50: 3.20E+4nM
Assay Description:
Inhibition of iNOS-mediated NO production in mouse RAW264.7 cells by Griess assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI