Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 295 hits in this display
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 6.70nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 8.70nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 10nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 10nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
BDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)IC50: 26nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM3180(3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-ind...)IC50: 31nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM3171(3-(1-methyl-1H-indol-3-yl)-4-{1-[3-(methylamino)pr...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM50313007(3-(1-methyl-1H-indol-3-yl)-4-(pyridin-3-yl)-1H-pyr...)
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
IC50: 45nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)IC50: 45nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)IC50: 52nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)IC50: 55nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM33964(maleimide derivative, 3)IC50: 60nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)IC50: 64nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)IC50: 70nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
IC50: 75nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)IC50: 76nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)IC50: 80nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM3173(Bisindolylmaleimide 9 | Trimethyl[3-[3-[3-(1-methy...)IC50: 93nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM33964(maleimide derivative, 3)
IC50: 98nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)IC50: 100nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
BDBM50132312(17,20-dimethyl-4,14,17,20,23-pentaazahexacyclo[21....)
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)IC50: 130nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 150nMpH: 7.6 T: 2°CAssay Description:A coupled-enzyme assay was used to quantify the ADP generated in the kinase reaction with S6 peptide (RRRLSSLRA) as the phosphoacceptorsubstrate.More data for this Ligand-Target Pair
BDBM33964(maleimide derivative, 3)
IC50: 165nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)IC50: 170nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 191nMAssay Description:Inhibition of GSK3beta (unknown origin) expressed in Sf9 cells using GS1 as substrate and [gamma32]ATP after 30 min by scinitllation countingMore data for this Ligand-Target Pair
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM33964(maleimide derivative, 3)
IC50: 207nMpH: 7.4 T: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM50132312(17,20-dimethyl-4,14,17,20,23-pentaazahexacyclo[21....)
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM50132312(17,20-dimethyl-4,14,17,20,23-pentaazahexacyclo[21....)
BDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
BDBM2626(3-(1,7-dimethyl-1H-indol-3-yl)-4-(1-methyl-1H-indo...)
BDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)IC50: 280nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)IC50: 300nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
BDBM33964(maleimide derivative, 3)
IC50: >315nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)IC50: 340nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM33964(maleimide derivative, 3)
IC50: 349nMT: 2°CAssay Description:Classical and novel PKC isotypes were assayed by scintillation proximity assay technology. In brief, the assay was performed in reaction buffer by in...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM153744(ROCHE screening, 55)IC50: 461nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
IC50: 469nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2593((Arylindolyl)maleimide deriv. 15 | 3-(1-methyl-1H-...)IC50: 480nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 500nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
IC50: 558nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
IC50: 620nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain expressed in bacteria using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
BDBM3180(3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-ind...)
IC50: 800nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2597((Arylindolyl)maleimide deriv. 19 | 3-(1-methyl-1H-...)IC50: 810nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM6771(3-(1H-indol-3-yl)-4-{1-[3-(methylamino)propyl]-1H-...)IC50: 960nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM50132318(3-(1-{2-[2-(2-Dimethylamino-ethoxy)-ethoxy]-ethyl}...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 990nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
IC50: 1.05E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)IC50: 1.17E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
IC50: 1.20E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2592((Arylindolyl)maleimide deriv. 14 | 3-(1-benzyl-1H-...)IC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
BDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
IC50: 1.20E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
IC50: 1.25E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50132315(17,20,23-trimethyl-4,14,17,20,23,26-hexaazahexacyc...)
BDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)IC50: 1.61E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
IC50: 1.80E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
BDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
IC50: 1.95E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM3171(3-(1-methyl-1H-indol-3-yl)-4-{1-[3-(methylamino)pr...)
IC50: 1.96E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
BDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
IC50: 2.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 2.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
BDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
IC50: 2.14E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
IC50: 2.50E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
IC50: 2.69E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)IC50: 2.75E+3nMAssay Description:The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...More data for this Ligand-Target Pair
BDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)
BDBM2598((Arylindolyl)maleimide deriv. 20 | 3-(1-methyl-1H-...)IC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM3179(3-(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-...)
IC50: 2.90E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
IC50: 3.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 3.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 3.40E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM6771(3-(1H-indol-3-yl)-4-{1-[3-(methylamino)propyl]-1H-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 3.80E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2593((Arylindolyl)maleimide deriv. 15 | 3-(1-methyl-1H-...)
IC50: 3.97E+3nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2602((Arylindolyl)maleimide deriv. 24 | 3-(1-Methyl-3-i...)
BDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
IC50: 4.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
IC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
IC50: 5.20E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
BDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
IC50: 5.70E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
IC50: 6.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
IC50: 6.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM3180(3-[1-(4-Amidinobutyl)-3-indolyl]-4-(1-methyl-3-ind...)
IC50: 7.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM2601((Arylindolyl)maleimide deriv. 23 | 3-(1-methyl-1H-...)IC50: 7.70E+3nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
BDBM3167(3-[1-(2-aminoethyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
IC50: 8.90E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
BDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
IC50: 9.30E+3nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)
IC50: >1.00E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CDK5/p25 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
IC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human PIM1 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 1.02E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
BDBM3170(3-[1-(5-aminopentyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
IC50: 1.04E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
BDBM2590((Arylindolyl)maleimide deriv. 12 | 3-(1H-indol-3-y...)
IC50: 1.17E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM3171(3-(1-methyl-1H-indol-3-yl)-4-{1-[3-(methylamino)pr...)
IC50: 1.19E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
IC50: 1.40E+4nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
BDBM3164(3-[1-(3-Hydroxypropyl)-3-indolyl]-4-(1-methyl-3-in...)
IC50: 1.42E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)
IC50: 1.47E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
IC50: 1.61E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM3165(3-[1-(4-hydroxybutyl)-1H-indol-3-yl]-4-(1-methyl-1...)
IC50: 1.84E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: 1.90E+4nMAssay Description:Inhibitory concentration was determined by measuring phoshporylation of H1 histone using active human Cell division cycle 2-cyclin B complexMore data for this Ligand-Target Pair
BDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
IC50: >2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
IC50: >2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
BDBM2601((Arylindolyl)maleimide deriv. 23 | 3-(1-methyl-1H-...)
BDBM3169(3-[1-(4-aminobutyl)-1H-indol-3-yl]-4-(1-methyl-1H-...)
IC50: >2.00E+4nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2597((Arylindolyl)maleimide deriv. 19 | 3-(1-methyl-1H-...)
IC50: >2.00E+4nMAssay Description:IC50 determinations for TBK1 were performed with the KinEASE-STK assay from Cisbio according to the manufacturer's instructions. A biotinylated s...More data for this Ligand-Target Pair
BDBM2591((Arylindolyl)maleimide deriv. 13 | 3,4-bis(1-methy...)
IC50: >2.00E+4nMT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...More data for this Ligand-Target Pair
BDBM3166(3-[1-(5-hydroxypentyl)-1H-indol-3-yl]-4-(1-methyl-...)
IC50: 2.13E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50070082(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-{1-...)IC50: 2.20E+4nMAssay Description:Inhibitory concentration was determined by measuring phoshporylation of H1 histone using active human Cell division cycle 2-cyclin B complexMore data for this Ligand-Target Pair
BDBM3163(3-[1-(2-hydroxyethyl)-1H-indol-3-yl]-4-(1-methyl-1...)
IC50: 2.21E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50167287(3-[1-(3-Amino-propyl)-1H-indol-3-yl]-4-(1H-indol-3...)
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
IC50: 2.56E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50313007(3-(1-methyl-1H-indol-3-yl)-4-(pyridin-3-yl)-1H-pyr...)
BDBM50070090(3-[1-(3-Dimethylamino-propyl)-1H-indol-3-yl]-4-(1-...)IC50: 3.50E+4nMAssay Description:Inhibitory concentration was determined by measuring phoshporylation of H1 histone using active human Cell division cycle 2-cyclin B complexMore data for this Ligand-Target Pair
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM3173(Bisindolylmaleimide 9 | Trimethyl[3-[3-[3-(1-methy...)
IC50: 6.45E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
BDBM50199956(3,4-bis(1-benzyl-1H-indol-3-yl)-1-methyl-1H-pyrrol...)
BDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
BDBM50199957(3,4-bis(1-(7-hydroxyheptyl)-1H-indol-3-yl)-1-methy...)
BDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
BDBM2597((Arylindolyl)maleimide deriv. 19 | 3-(1-methyl-1H-...)
IC50: >1.00E+5nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2592((Arylindolyl)maleimide deriv. 14 | 3-(1-benzyl-1H-...)
IC50: >1.00E+5nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
BDBM50199955(3,4-bis(1-heptyl-1H-indol-3-yl)-1-methyl-1H-pyrrol...)
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2601((Arylindolyl)maleimide deriv. 23 | 3-(1-methyl-1H-...)
IC50: >1.00E+5nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
BDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
BDBM2695(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H...)
BDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
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