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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Cholesterol side-chain cleavage enzyme, mitochondrial
(Rattus norvegicus)
Lucknow University
Curated by
ChEMBL
Ligand
BDBM50476074
(Gentamicin | SCH-9724 | Uromycine)
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Affinity Data
IC50: 445nM
Assay Description:
Antibacterial activity against Streptococcus faecalis by broth microdilution technique
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
NH(3)-dependent NAD(+) synthetase
(Bacillus subtilis)
University Of Alabama At Birmingham
Curated by
ChEMBL
Ligand
BDBM50366389
(GENTAMICIN)
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Affinity Data
IC50: >1.00E+3nM
Assay Description:
Inhibitory activity against Bacillus subtilis NAD synthetase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Dihydrofolate reductase
(Homo sapiens (Human))
King Saud University
Curated by
ChEMBL
Ligand
BDBM50366389
(GENTAMICIN)
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Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of human DHFR after 2 mins
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Dihydrofolate reductase
(Bos taurus (Cattle))
King Saud University
Curated by
ChEMBL
Ligand
BDBM50366389
(GENTAMICIN)
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Affinity Data
IC50: 2.50E+4nM
Assay Description:
Inhibition of bovine DHFR after 2 mins
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
Acyl-protein thioesterase 1
(Rattus norvegicus)
Katholieke Universiteit Leuven
Curated by
ChEMBL
Ligand
BDBM50011926
(4-amino-2-[2,4-diamino-5-(3-amino-6-aminomethyl-4,...)
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Affinity Data
IC50: 7.90E+4nM
Assay Description:
in vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts. p<0.05
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Phospholipase A1 member A
(Rattus norvegicus)
Agricultural University Of Athens
Curated by
ChEMBL
Ligand
BDBM50366389
(GENTAMICIN)
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Affinity Data
IC50: 9.42E+4nM
Assay Description:
IC50 was measured as concentration causing 50% inhibition of lysosomal phospholipase A1 activity.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI