Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 48 hits in this display
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM595126(US11584714, Compound 1156)
BDBM595086(US11584714, Compound 1114)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595086(US11584714, Compound 1114)
BDBM595074(US11584714, Compound 1102)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595055(US11584714, Compound 1083)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595055(US11584714, Compound 1083)
Ki: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM595049(US11584714, Compound 1077)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595024(US11584714, Compound 1051)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM594999(US11584714, Compound 1026)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM594990(US11584714, Compound 1017)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM594990(US11584714, Compound 1017)
Ki: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM594981(US11584714, Compound 1008)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595128(US11584714, Compound 1158)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM594975(US11584714, Compound 1002)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Ki: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Ki: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Ki: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM594981(US11584714, Compound 1008)
Ki: 1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM595074(US11584714, Compound 1102)
Ki: 1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM594999(US11584714, Compound 1026)
Ki: 1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM594991(US11584714, Compound 1018)
Ki: 6.25E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM594991(US11584714, Compound 1018)
Ki: 6.25E+3nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
BDBM595049(US11584714, Compound 1077)
Ki: 6.25E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM594975(US11584714, Compound 1002)
Ki: 6.25E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM595024(US11584714, Compound 1051)
Ki: 6.25E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM595126(US11584714, Compound 1156)
Ki: 1.75E+4nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM595128(US11584714, Compound 1158)
Ki: 1.75E+4nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)
BDBM29388(Exanta | Melagatran | US11584714, Compound 999)