Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 44 hits in this display   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115867(2-(2-Hydroxy-3-phenoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  400nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115870(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  700nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115867(2-(2-Hydroxy-3-phenoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  1.10E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.72 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115870(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115867(2-(2-Hydroxy-3-phenoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  2.50E+3nM ΔG°:  -31.7kJ/molepH: 7.5 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115870(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  3.60E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.60E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  3.60E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  4.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115867(2-(2-Hydroxy-3-phenoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  6.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  6.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  6.60E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  6.70E+3nM ΔG°:  -29.2kJ/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50115870(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  8.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  8.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  8.90E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.40E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14357(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  9.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM14357(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  1.10E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50115867(2-(2-Hydroxy-3-phenoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50115870(2-(3-Ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13939(2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5...)
Affinity DataKi:  4.10E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM14357(2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2...)
Affinity DataKi:  4.90E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102782(2-(2-Hydroxy-5-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  6.90E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102788(2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed