Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandBDBM11442(5-chloro-N-(4-methanesulfonylphenyl)pyrazolo[1,5-a...)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoDrugBankPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
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TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Martin-Luther-University Halle-Wittenberg

LigandBDBM11442(5-chloro-N-(4-methanesulfonylphenyl)pyrazolo[1,5-a...)Copy SMILESCopy InChI

Affinity DataIC50:  3.10E+3nMT: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoDrugBankPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI