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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Cereblon isoform 4
(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
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Affinity Data
Ki: 1.07E+4nM
Assay Description:
Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assay
More data for this Ligand-Target Pair
Target Info
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Target
Protein cereblon
(Homo sapiens (Human))
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
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Affinity Data
Ki: 1.37E+5nM
Assay Description:
Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...
More data for this Ligand-Target Pair
Target Info
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Target
Cereblon isoform 4
(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.70E+6nM
Assay Description:
Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
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Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Cereblon isoform 4
(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10E+7nM
Assay Description:
Competitive binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST ba...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
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PC sid
PDB
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Choline O-acetyltransferase
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
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Affinity Data
Ki: 2.50E+7nM
Assay Description:
Compound was evaluated for reversible inhibition of hydrolysis acetylcholine by acetylcholinesterase and represented as KI(com)
More data for this Ligand-Target Pair
Target Info
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B.MOAD
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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PC sid
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Article
PubMed
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Target
Protein cereblon
(Homo sapiens (Human))
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.37E+8nM
Assay Description:
Competitive binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cereblon isoform 4
(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.08E+4nM
Assay Description:
Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Protein cereblon
(Homo sapiens (Human))
Max Planck Institute For Developmental Biology
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.64E+5nM
Assay Description:
Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Biofilm regulatory protein A
(Streptococcus mutans serotype c (strain ATCC 70061...)
Uab Research Foundation
US Patent
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
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Affinity Data
IC50: >5.00E+5nM
Assay Description:
A previously reported zymographic assay was utilized for the investigation of Gtf enzymatic activity, as described in Example 1. A 1:100 in fresh 5 m...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
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US Patent
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Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
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Affinity Data
Kd: 6.48E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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antibodypedia
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ChEBI
CHEMBL
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KEGG
MMDB
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5.41E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.50E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7.19E+8nM
Assay Description:
Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
MMDB
PC cid
PC sid
PDB
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.10E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 7.83E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Insulin-like growth factor-binding protein 5
(Homo sapiens (Human))
Institute For Biochemistry
Curated by
ChEMBL
Ligand
BDBM50026472
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 9.21E+8nM
Assay Description:
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
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PC cid
PC sid
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Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI