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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Riboflavin-binding protein
(Gallus gallus)
Calvin College
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
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Affinity Data
Ki: 350nM
Assay Description:
Competitive inhibition of chicken riboflavin binding protein by surface plasmon resonance assay
More data for this Ligand-Target Pair
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Target
Thiosulfate sulfurtransferase
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50523758
(Phosphated riboflavin | Photrexa | RIBOFLAVIN 5'-P...)
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Affinity Data
IC50: 380nM
Assay Description:
Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...
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Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50523758
(Phosphated riboflavin | Photrexa | RIBOFLAVIN 5'-P...)
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Affinity Data
IC50: 770nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...
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Target
Thiosulfate sulfurtransferase
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.80E+3nM
Assay Description:
Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...
More data for this Ligand-Target Pair
Target Info
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Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
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Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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Target
60 kDa heat shock protein, mitochondrial
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50523758
(Phosphated riboflavin | Photrexa | RIBOFLAVIN 5'-P...)
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Affinity Data
IC50: 8.00E+4nM
Assay Description:
Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
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PC cid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50523758
(Phosphated riboflavin | Photrexa | RIBOFLAVIN 5'-P...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.50E+4nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
60 kDa heat shock protein, mitochondrial
(Homo sapiens)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
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MCE
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Co-chaperonin GroES
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Chaperonin GroEL
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50523758
(Phosphated riboflavin | Photrexa | RIBOFLAVIN 5'-P...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Chaperonin GroEL
(Escherichia coli)
Indiana University School Of Medicine
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+5nM
Assay Description:
Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Riboflavin-binding protein
(Gallus gallus)
Calvin College
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
Kd: 46nM
pH: 4.0
Assay Description:
Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 4 in 0.1 M NaAc by isothermal titration calorimetric a...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
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MCE
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Riboflavin-binding protein
(Gallus gallus)
Calvin College
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.60nM
pH: 7.4
Assay Description:
Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in 0.1 M phosphate buffer by isothermal titration ...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Riboflavin-binding protein
(Gallus gallus)
Calvin College
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5nM
pH: 7.4
Assay Description:
Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in phosphate buffer by isothermal titration calori...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Patents
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Riboflavin-binding protein
(Gallus gallus)
Calvin College
Curated by
ChEMBL
Ligand
BDBM50362895
(Lactoflavin | RIBOFLAVIN)
Copy SMILES
Copy InChI
Affinity Data
Kd: 34nM
pH: 9.0
Assay Description:
Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 9 in 0.1 M Tris by isothermal titration calorimetric a...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Chorismate synthase
(Streptococcus pneumoniae)
TBA
Curated by
ChEMBL
Ligand
BDBM50421345
(E101a | RIBOFLAVIN 5'-PHOSPHATE | Riboflavin 5''-P...)
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Affinity Data
Kd: >2.00E+4nM
Assay Description:
Compound was evaluated for the binding affinity towards Escherichia coli chorismate synthase
More data for this Ligand-Target Pair
Target Info
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MMDB
KEGG
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3D Structure (crystal)
Copy BDB DOI