Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandBDBM93009(Glutamine Analogue, 1)Copy SMILESCopy InChI

Affinity DataKi:  5.40E+4nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseChEBI
MCE
KEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent

LigandBDBM181129(US9138393, D-Glutamine | US9144538, D-Glutamine)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
KEGGPC cidPC sidPDBSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent

LigandBDBM18121((2S)-2-amino-4-carbamoylbutanoic acid | CHEMBL930 ...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
KEGGMMDBPC cidPC sidPDBSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent

LigandBDBM18121((2S)-2-amino-4-carbamoylbutanoic acid | CHEMBL930 ...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
KEGGMMDBPC cidPC sidPDBSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
The Procter & Gamble

US Patent

LigandBDBM181129(US9138393, D-Glutamine | US9144538, D-Glutamine)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMCE
KEGGPC cidPC sidPDBSimilars

In DepthDetails US Patent
Copy BDB DOI