Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Glutathione reductase, mitochondrial
(Homo sapiens (Human))
Batman University
Curated by
ChEMBL
Ligand
BDBM50352165
(LYSINE)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.46E+4nM
Assay Description:
Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Isoleucine--tRNA ligase
(Escherichia coli)
Gesellschaft Fur Molekularbiolische Forschung Mbh
Ligand
BDBM18139
((2S)-2-aminoheptanoic acid | L-2-Amino-heptanoic a...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.67E+7nM ΔG°: -9.98kJ/mole
pH: 7.5 T: 2°C
Assay Description:
Utilizing an analytical ultracentrifuge, the binding constants of various amino acids and isoleucine analogues to IleRS were estimated from their com...
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bifunctional aspartokinase/homoserine dehydrogenase 1
(Escherichia coli)
University Of Akron
Ligand
BDBM92991
(L-norleucine)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+7nM
Assay Description:
Analogues of L-aspartic acid and beta-aspartyl phosphate were examined as inhibitors in the aspartokinase I reaction by using the coupled reaction wi...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glutathione reductase, mitochondrial
(Homo sapiens (Human))
Batman University
Curated by
ChEMBL
Ligand
BDBM50352165
(LYSINE)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.12E+4nM
Assay Description:
Inhibition of human erythrocyte Glutathione reductase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052549
(2-Amino-heptanedioic acid | CHEMBL111050)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu6 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052549
(2-Amino-heptanedioic acid | CHEMBL111050)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu1-alpha receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052552
(2-Amino-octanedioic acid | CHEMBL320957)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu6 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052552
(2-Amino-octanedioic acid | CHEMBL320957)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052549
(2-Amino-heptanedioic acid | CHEMBL111050)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Arginase-1
(Homo sapiens (Human))
Drexel University
Curated by
ChEMBL
Ligand
BDBM50354832
(CHEMBL1834160)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.00E+4nM
Assay Description:
Displacement of [14C-guanidino]-L-arginine from human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
APC family lysine-specific permease
(Salmonella typhimurium)
Max Planck Institute Of Biophysics
Ligand
BDBM217368
((2R)-2,6-diaminohexanoic acid | D-Lysine)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.80E+6nM
pH: 5.9 T: 2°C
Assay Description:
ITC measurements were carried out at 20 °C with a VP-ITC calorimeter (GE Healthcare, MicroCal, Inc.) consisting of a 1.45-ml reaction cell. STM2200 i...
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
KEGG
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
APC family lysine-specific permease
(Salmonella typhimurium)
Max Planck Institute Of Biophysics
Ligand
BDBM217367
((2S)-2,6-diaminohexanoic acid | L-Lysine)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.00E+4nM
pH: 5.9 T: 2°C
Assay Description:
ITC measurements were carried out at 20 °C with a VP-ITC calorimeter (GE Healthcare, MicroCal, Inc.) consisting of a 1.45-ml reaction cell. STM2200 i...
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
DrugBank
KEGG
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Royal Danish School Of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50052552
(2-Amino-octanedioic acid | CHEMBL320957)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Agonistic activity at mGlu1-alpha receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI