Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetTubulin--tyrosine ligase(Homo sapiens (Human))
Binghamton University

LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
Affinity DataKi:  2.50E+4nM ΔG°:  -27.3kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
China Pharmaceutical University

US Patent
LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
Affinity DataIC50: >6.00E+4nMAssay Description:11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18129((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
Affinity DataIC50:  6.80E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50463198(CHEBI:28479 | CHEMBL1076637 | D-Tyrosine)
Affinity DataIC50:  3.80E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrp operon repressor(Escherichia coli (strain K12))
University Of Chicago

LigandPNGBDBM92702(L-Tyrosine, 24)
Affinity DataKd: >3.00E+6nMAssay Description:Binding assay of L-trptophan and analogues to trp aporepressorMore data for this Ligand-Target Pair
In DepthDetails PubMed