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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
Tubulin--tyrosine ligase
(Homo sapiens (Human))
Binghamton University
Ligand
BDBM18129
((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
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Affinity Data
Ki: 2.50E+4nM ΔG°: -27.3kJ/mole
pH: 6.8 T: 2°C
Assay Description:
Inhibition of [3H]-L-tyrosine incorporation into tubulin by enzyme tubulin tyrosine ligase (TTL).
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Target Info
PDB
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KEGG
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B.MOAD
antibodypedia
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Target
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human))
China Pharmaceutical University
US Patent
Ligand
BDBM18129
((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
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Affinity Data
IC50: >6.00E+4nM
Assay Description:
11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m...
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Target Info
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KEGG
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B.MOAD
DrugBank
antibodypedia
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ChEBI
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US Patent
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Target
Large neutral amino acids transporter small subunit 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM18129
((2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L...)
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Affinity Data
IC50: 6.80E+4nM
Assay Description:
Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...
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Target Info
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
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ChEBI
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Target
Large neutral amino acids transporter small subunit 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50463198
(CHEBI:28479 | CHEMBL1076637 | D-Tyrosine)
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Affinity Data
IC50: 3.80E+5nM
Assay Description:
Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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KEGG
PC cid
PC sid
PDB
In Depth
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Article
PubMed
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Target
Trp operon repressor
(Escherichia coli (strain K12))
University Of Chicago
Ligand
BDBM92702
(L-Tyrosine, 24)
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Affinity Data
Kd: >3.00E+6nM
Assay Description:
Binding assay of L-trptophan and analogues to trp aporepressor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
KEGG
PC cid
PC sid
Similars
In Depth
Details
PubMed
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