Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 64 hits in this display   

TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  65nM ΔG°:  -40.6kJ/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  170nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  280nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  750nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory concentration against Human Serine Protease Urokinase Plasminogen ActivatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  2.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  2.30E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  3.40E+3nM ΔG°:  -30.9kJ/molepH: 7.72 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  3.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  3.60E+3nM ΔG°:  -30.8kJ/molepH: 7.7 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.60E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  3.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.90E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  4.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  5.50E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  6.00E+3nMAssay Description:Activity against Human Serine Protease TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  6.70E+3nM ΔG°:  -29.2kJ/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of Human Serine Protease PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  7.50E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  8.00E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  8.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  8.90E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.40E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.90E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  1.10E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Bos taurus)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13943(APC-1847 | {amino[2-(2-methoxyphenyl)-1H-1,3-benzo...)
Affinity DataKi:  1.70E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  1.70E+4nMAssay Description:Activity against Human Serine Protease ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102774(2-(2,6-Dihydroxy-phenyl)-1H-benzoimidazole-5-carbo...)
Affinity DataKi:  2.50E+4nMAssay Description:Inihibtion of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease hepsin(Homo sapiens (Human))
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102775(2-(2-Hydroxy-4-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  5.50E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  6.30E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102772(2-(2-Hydroxy-3-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.90E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102793(2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.13E+5nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSporulation kinase A(Bacillus subtilis (strain 168))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50100897(2-(2-Hydroxy-phenyl)-1H-benzoimidazole-5-carboxami...)
Affinity DataIC50:  4.70E+5nMAssay Description:Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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