Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 24 hits in this display   

TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  0.670nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  0.710nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093062((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  12.4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50084007((S)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  20.6nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  28.8nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093062((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  163nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against Human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  329nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50:  1.55E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50084007((S)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against coagulation factor II (thrombin).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093062((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50: >2.50E+3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50093062((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Affinity DataIC50:  3.83E+3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against Thrombin (FIIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  6.07E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Affinity DataIC50:  6.48E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed