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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
24
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054486
(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
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Affinity Data
IC50: 0.670nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
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In Depth
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Article
PubMed
PDB
3D Structure (crystal)
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Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054484
(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
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Affinity Data
IC50: 0.710nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50093062
((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
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Affinity Data
IC50: 1.90nM
Assay Description:
Inhibitory activity against Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054488
(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12.4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50084007
((S)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibitory activity against coagulation factor X.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054484
(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
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Copy InChI
Affinity Data
IC50: 20.6nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054485
(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
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Copy InChI
Affinity Data
IC50: 28.8nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine protease 1
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50093062
((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
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Affinity Data
IC50: 163nM
Assay Description:
Compound was evaluated in vitro for its inhibitory activity against Human trypsin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054484
(CHEMBL344204 | CVS-1778 | N-((S)-1-Formyl-4-guanid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 329nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054488
(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.55E+3nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50084007
((S)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibitory activity against coagulation factor II (thrombin).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054488
(CHEMBL138441 | CVS-1178 | N-((S)-1-Formyl-4-guanid...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50093062
((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+3nM
Assay Description:
Compound was evaluated in vitro for its inhibitory activity against plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50093062
((R)-5-Guanidino-2-phenylmethanesulfonylamino-penta...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.83E+3nM
Assay Description:
Compound was evaluated in vitro for its inhibitory activity against Thrombin (FIIa)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.51E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054487
(CHEMBL342914 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.51E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054486
(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054485
(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.50E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054485
(CHEMBL342604 | N-[(S)-1-((R)-1-Carbamimidoyl-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.07E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Anionic trypsin
(Bos taurus)
Corvas International
Curated by
ChEMBL
Ligand
BDBM50054486
(CHEMBL141424 | N-[(S)-1-((S)-1-Carbamimidoyl-piper...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.48E+4nM
Assay Description:
Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsin
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI