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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50010065(CHEMBL563834)
Affinity DataKi:  4.73E+3nMAssay Description:Competitive reversible inhibition of bovine thrombin using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after 15 to 40 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50009967(CHEMBL417907)
Affinity DataKi:  7.83E+3nMAssay Description:Competitive reversible inhibition of bovine thrombin using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after 15 to 40 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlandular kallikrein(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50009967(CHEMBL417907)
Affinity DataKi:  1.53E+4nMAssay Description:Competitive reversible inhibition of porcine pancreatic kallikrein using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  5.50E+4nMAssay Description:Compound was tested against Human Serine Protease TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  5.50E+4nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlandular kallikrein(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50010065(CHEMBL563834)
Affinity DataKi:  6.45E+4nMAssay Description:Competitive reversible inhibition of porcine pancreatic kallikrein using alpha-N-benzoyl-DL-arginine-p-nitroanilide hydrochloride as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  1.25E+5nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.50E+5nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataKi:  3.81E+5nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSporulation kinase A(Bacillus subtilis (strain 168))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218650(CHEMBL2114423)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSporulation kinase A(Bacillus subtilis (strain 168))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218657(CHEMBL289173)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSporulation kinase A(Bacillus subtilis (strain 168))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50100891(2-Phenyl-1H-benzoimidazole-5-carboxamidine | 2-Phe...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of KinA/Sp0F system two component (TCS) from Bacillus subtilis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed