Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225008(2-(4-(2-(1-benzoylpiperidin-4-yl)ethoxy)phenyl)-1H...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225011(2-(4-((1-benzylpiperidin-3-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224988(2-(4-((1-benzoylpiperidin-4-yl)methoxy)phenyl)-1H-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225006(2-(4-((1-(4-methoxybenzyl)piperidin-3-yl)methoxy)p...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224998(2-{4-[1-(4-methyl-benzyl)-piperidin-3-ylmethoxy]-p...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224993(2-(4-((1-(4-chlorobenzyl)piperidin-4-yl)methoxy)ph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225018(2-(4-((1-(4-methoxybenzyl)piperidin-4-yl)methoxy)p...)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224986(2-{4-[1-(4-methyl-benzyl)-piperidin-4-ylmethoxy]-p...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225019(2-(4-((1-benzylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224990(2-(4-((1-acetylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50:  78nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224989(2-(4-(2-(1-(4-chlorobenzyl)piperidin-4-yl)ethoxy)p...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224996(2-(4-{2-[1-(4-methyl-benzyl)-piperidin-4-yl]-ethox...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50224987(2-(4-(2-(1-benzylpiperidin-4-yl)ethoxy)phenyl)-1H-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225020(2-(4-(2-(1-(4-methoxybenzyl)piperidin-4-yl)ethoxy)...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225007(2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225013(2-(4-((1-(3,4-dichlorobenzyl)piperidin-4-yl)methox...)
Affinity DataIC50:  176nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50225004(2-(4-(piperidin-4-ylmethoxy)phenyl)-1H-benzo[d]imi...)
Affinity DataIC50:  231nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair