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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225008
(2-(4-(2-(1-benzoylpiperidin-4-yl)ethoxy)phenyl)-1H...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225011
(2-(4-((1-benzylpiperidin-3-yl)methoxy)phenyl)-1H-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224988
(2-(4-((1-benzoylpiperidin-4-yl)methoxy)phenyl)-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225006
(2-(4-((1-(4-methoxybenzyl)piperidin-3-yl)methoxy)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224998
(2-{4-[1-(4-methyl-benzyl)-piperidin-3-ylmethoxy]-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 57nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224993
(2-(4-((1-(4-chlorobenzyl)piperidin-4-yl)methoxy)ph...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225018
(2-(4-((1-(4-methoxybenzyl)piperidin-4-yl)methoxy)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224986
(2-{4-[1-(4-methyl-benzyl)-piperidin-4-ylmethoxy]-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225019
(2-(4-((1-benzylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224990
(2-(4-((1-acetylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 78nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224989
(2-(4-(2-(1-(4-chlorobenzyl)piperidin-4-yl)ethoxy)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 82nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224996
(2-(4-{2-[1-(4-methyl-benzyl)-piperidin-4-yl]-ethox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50224987
(2-(4-(2-(1-benzylpiperidin-4-yl)ethoxy)phenyl)-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225020
(2-(4-(2-(1-(4-methoxybenzyl)piperidin-4-yl)ethoxy)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 95nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225007
(2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225013
(2-(4-((1-(3,4-dichlorobenzyl)piperidin-4-yl)methox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 176nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by
ChEMBL
Ligand
BDBM50225004
(2-(4-(piperidin-4-ylmethoxy)phenyl)-1H-benzo[d]imi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 231nM
Assay Description:
Inhibition of human recombinant Chk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI