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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT)
University Of Kansas
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Ki: 9.10E+3nM
Assay Description:
Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptor
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Target
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine))
University Of Kansas
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Ki: 2.35E+4nM
Assay Description:
Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)
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Target
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine))
University Of Kansas
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Ki: 1.70E+5nM
Assay Description:
Inhibition of bovine PNMT by radiochemical assay
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Target
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine))
University Of Kansas
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Ki: 1.79E+5nM
Assay Description:
In vitro for inhibition of Phenylethanolamine N-Methyltransferase (PNMT)
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Target
Serine protease 1
(Homo sapiens (Human))
Czech Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Ki: 3.00E+8nM
Assay Description:
The compound was tested for inhibition of the proteolytic enzyme trypsin.
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Target
Serine protease 1
(Homo sapiens (Human))
Czech Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50408785
(CHEMBL273483)
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Affinity Data
Ki: 6.66E+8nM
Assay Description:
The compound was tested for inhibition of the proteolytic enzyme trypsin.
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Target
Replicase polyprotein 1ab
(2019-nCoV)
Cornell University
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
IC50: 61nM
Assay Description:
IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).
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Target
Replicase polyprotein 1ab
(2019-nCoV)
Cornell University
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
IC50: 100nM
Assay Description:
IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).
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Target
Lysyl oxidase homolog 2
(Homo sapiens (Human))
Pharmakea
Curated by
ChEMBL
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
IC50: 6.47E+4nM
Assay Description:
Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...
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Target
Urease subunit alpha
(Helicobacter pylori ATCC43504)
Wuhan Textile University
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
IC50: >1.00E+5nM
pH: 7.4 T: 2°C
Assay Description:
Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...
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Host:
BDBM197310
(SAMPL5, CBClip)
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University Of California San Diego
Ligand
BDBM197288
(SAMPL4, C1 | SAMPL5, CBC-G1)
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Affinity Data
Kd: 5.26E+4nM
pH: 7.4 T: 2°C
Assay Description:
The experimental studies were carried out in 20 mM sodium phosphate buffer at pH7.4, at a temperature of 298 K.
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Target
Cytochrome P450 130
(Mycobacterium tuberculosis)
University Of California San Francisco
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Kd: 1.00E+7nM
Assay Description:
Binding assay using CYP130, CYP130 (G234) or CYP142.
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Target
Steroid C26-monooxygenase
(Mycobacterium tuberculosis)
University Of California San Francisco
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Kd: 100nM
Assay Description:
Binding assay using CYP130, CYP130 (G234) or CYP142.
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Target
Cytochrome P450 130
(Mycobacterium tuberculosis)
University Of California San Francisco
Ligand
BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)
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Affinity Data
Kd: 9.99E+6nM
Assay Description:
Binding assay using CYP130, CYP130 (G234) or CYP142.
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