Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 14 hits in this display
BDBM11453(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
BDBM11454(5-N-(4-aminocyclohexyl)-7-N-(4-methanesulfonylphen...)IC50: 250nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11455(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)IC50: 260nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11452(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)IC50: 270nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11449(4-{[5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a]pyri...)IC50: 730nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11452(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
BDBM11449(4-{[5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a]pyri...)
IC50: 970nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
BDBM11455(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)
IC50: 4.30E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11453(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
IC50: 5.60E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11450(4-({5-[(4-hydroxycyclohexyl)amino]-[1,2,4]triazolo...)IC50: 7.40E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11454(5-N-(4-aminocyclohexyl)-7-N-(4-methanesulfonylphen...)
IC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
BDBM11453(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
IC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
BDBM11454(5-N-(4-aminocyclohexyl)-7-N-(4-methanesulfonylphen...)
IC50: 4.30E+4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
BDBM11455(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)
IC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair