Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataKi:  299nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataIC50:  613nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataIC50:  821nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12018(2,5-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,5-DIFLU...)
Affinity DataKd:  2.20nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12021(2,4,6-trifluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,4,6-...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12017(2,4-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,4-DIFLU...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12016(2,3-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,3-DIFLU...)
Affinity DataKd:  1.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12015(4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZA...)
Affinity DataKd:  3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12014(2-fluoro-SBB | 4-(AMINOSULFONYL)-N-[(2-FLUOROPHENY...)
Affinity DataKd:  2.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University Of Pennsylvania

LigandPNGBDBM12019(2,6-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,6-DIFLU...)
Affinity DataKd:  3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair