Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 11 hits in this display
IC50: 613nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
IC50: 821nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
BDBM12018(2,5-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,5-DIFLU...)
BDBM12021(2,4,6-trifluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,4,6-...)
Kd: 3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
BDBM12017(2,4-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,4-DIFLU...)
Kd: 3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
BDBM12016(2,3-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,3-DIFLU...)
Kd: 1.60nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
BDBM12015(4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZA...)
Kd: 3.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
BDBM12014(2-fluoro-SBB | 4-(AMINOSULFONYL)-N-[(2-FLUOROPHENY...)
Kd: 2.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
BDBM12019(2,6-difluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,6-DIFLU...)
Kd: 3.90nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair