Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 49 hits in this display
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM50010318(CHEBI:17345 | CHEMBL283807)
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM50326433(((2R,3R,4S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM81822(CAS_6804 | GMP | Guanosine | NSC_6804)
BDBM50010318(CHEBI:17345 | CHEMBL283807)
IC50: 2.90nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
IC50: 4.20nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
RocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)University Of Maryland
Curated by ChEMBL
RocR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)University Of Maryland
Curated by ChEMBL
IC50: 6.41E+3nMAssay Description:Competitive binding affinity to Pseudomonas aeruginosa PAO1 His6-tagged RocR expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of [32...More data for this Ligand-Target Pair
BDBM50165117(2-amino-6-hydroxy-9-[(2R,4S,5R)-5-[(phosphinatooxy...)
BDBM426061(US10513520, Compound GMP | guanosine monophosphate)
Kd: 9.65E+3nMAssay Description:Binding affinity to wild-type human STING-CTD (139-379) expressed in Escherichia coli BL21(D Escherichia ) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
BDBM50326433(((2R,3R,4S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
BDBM573842((5R,7R,8R,12aR,14R,15R,15aS,18R)-7-(2-amino- 6-oxo...)
BDBM573860(2-amino-9-[(5S,7R,8R,12aR,14R,15R,15aS)-14- (6-ami...)
EC50: 2.40nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
BDBM573998(2-amino-9- [(2aR,6aS,7R,8R,9aR,14R,14aS,15R)- 5,7,...)
EC50: 2.32E+3nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
BDBM573842((5R,7R,8R,12aR,14R,15R,15aS,18R)-7-(2-amino- 6-oxo...)
BDBM50326433(((2R,3R,4S,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)