Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)
Affinity DataKi:  18nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)
Affinity DataKi: >2.90E+3nM ΔG°: >-31.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14057(N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-te...)
Affinity DataKi: >4.00E+3nM ΔG°: >-30.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed