Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 302 hits in this display
BDBM50023910(({[({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-y...)
BDBM50023910(({[({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-y...)
BDBM50205417(CHEMBL220200 | UTP-gamma-S)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)Ki: 3.70E+3nMAssay Description:Evaluated for the mixed objective Non-competitive inhibition constant Ki against TdR varied rat mitochondrial thymidine kinaseMore data for this Ligand-Target Pair
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50096295(Uridine | Uridine dinucleoside 5'-polyphosphate an...)
BDBM50096295(Uridine | Uridine dinucleoside 5'-polyphosphate an...)
BDBM50096295(Uridine | Uridine dinucleoside 5'-polyphosphate an...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
IC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM642791(US11857560, I.D. ENUC-01890)
BDBM642791(US11857560, I.D. ENUC-01890)
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
IC50: 5.00E+3nMAssay Description:Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 minsMore data for this Ligand-Target Pair
IC50: 5.50E+3nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
IC50: 3.60E+4nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
IC50: 3.60E+4nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50319138(CHEMBL1083258 | P1-Uridine 5'-P3-Cyclohexyltriphos...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)EC50: 1.31E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 1.65E+4nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)EC50: 1.70E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)EC50: 4.00E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 55nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50341879(CHEMBL1767408 | Diquafosol)
EC50: 210nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50179185(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H...)
EC50: 5.16E+6nMAssay Description:Agonist activity at recombinant human P2Y14 receptor expressed in African green monkey COS7 cells co-transfected with Galphaqi assessed as stimulatio...More data for this Ligand-Target Pair
BDBM50209658(CHEMBL390160 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)EC50: 1.88E+3nMAssay Description:Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsisMore data for this Ligand-Target Pair
BDBM50209661(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
BDBM50304038(CHEMBL594065 | Diphosphoric Acid 1''-alpha-D-[6'']...)
BDBM50304039(CHEMBL596145 | Diphosphoric Acid 1''-alpha-D-[6'']...)
BDBM50304040(CHEMBL595467 | Diphosphoric Acid 1''-alpha-D-[5'']...)
BDBM50304041(CHEMBL593842 | Diphosphoric Acid 1''-alpha-D-[5'']...)
BDBM50209661(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
BDBM50304042(CHEMBL604676 | Diphosphoric Acid 1''-alpha-D-[1'']...)
BDBM50304043(CHEMBL593346 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
BDBM50179185(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H...)
BDBM50319138(CHEMBL1083258 | P1-Uridine 5'-P3-Cyclohexyltriphos...)
EC50: 6.99E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
EC50: 270nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 300nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)EC50: 15nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50318022(CHEMBL1096401 | uridine diphosphate trisodium salt)
BDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
EC50: 945nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
EC50: 7.60E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)
EC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production after 30 mins by sc...More data for this Ligand-Target Pair
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 88nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 6.00E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate intracellular accumulation by ...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 300nMAssay Description:The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50184367(CHEMBL373774 | [bis({[(2R,3S,4R,5R)-5-(2,4-dioxo-1...)
BDBM50184369(CHEMBL413131 | pentakis(tributylamine) boranuidyl(...)
BDBM50184369(CHEMBL413131 | pentakis(tributylamine) boranuidyl(...)
BDBM50184369(CHEMBL413131 | pentakis(tributylamine) boranuidyl(...)
BDBM50199173(((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...)
BDBM50199173(((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...)
BDBM50199173(((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50199183(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50194162(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50199190(3-METHYLURIDINE-5'-MONOPHOSHATE | 3-methyl-1-beta-...)
BDBM50194162(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50199183(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50199183(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50194162(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
BDBM50199190(3-METHYLURIDINE-5'-MONOPHOSHATE | 3-methyl-1-beta-...)
BDBM50199173(((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...)
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 13nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194152((2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxym...)EC50: 15nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50179185(((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H...)
EC50: 1.72E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194157(CHEMBL378445 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)EC50: 2.30E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194161((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...)EC50: 3.10E+3nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194162(3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dion...)
EC50: 3.30E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194161((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...)
EC50: 810nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50194161((2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxyt...)
EC50: 2.50E+3nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as PLC-mediated [3H]IP productionMore data for this Ligand-Target Pair
BDBM50205409(({[({[(2R,3S,4R,5R)-5-(5-amino-2,4-dioxo-1,2,3,4-t...)EC50: 5.60E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205412(2'-methoxy-UTP | CHEMBL220337)EC50: 1.43E+4nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
EC50: 130nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
EC50: 480nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
EC50: 210nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
EC50: 2.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
EC50: 140nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205416(2'-deoxyuridine 5'-(tetrahydrogen triphosphate) | ...)EC50: 1.08E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
EC50: 3.90E+3nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205409(({[({[(2R,3S,4R,5R)-5-(5-amino-2,4-dioxo-1,2,3,4-t...)
EC50: 333nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205417(CHEMBL220200 | UTP-gamma-S)
EC50: 240nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50205418(CHEMBL410594 | uridine 5'-tetraphosphate 5'-ribose)EC50: 1.88E+3nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 1.93E+3nMAssay Description:Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluo...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 140nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
BDBM50306706(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methoxy-2,4-diox...)
BDBM50306707(((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropy...)
BDBM50306707(((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropy...)
BDBM50306707(((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropy...)
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
EC50: 100nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
BDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
BDBM50199173(((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyr...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50271101(CHEMBL488132 | [(2R,3S,4R,5R)-5-(5-amino-2,4-dioxo...)EC50: 610nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
EC50: 1.31E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270548(CHEMBL454230 | Uridine-5'-(2'-deoxy-glucose)-6'-te...)EC50: 3.54E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270547(CHEMBL508122 | Uridine-5'-mannose-6'-tetraphosphat...)EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270544(CHEMBL500840 | Uridine-5'-fructose-6'-tetraphospha...)EC50: 3.33E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270543(CHEMBL448985 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)EC50: 1.88E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270542(CHEMBL474887 | Uridine-5'-cyclohexane-tetraphospha...)EC50: 5.86E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271292(CHEMBL482895 | Uridine-5'-alpha-glycerol-tetraphos...)EC50: 1.87E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)
EC50: 1.70E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271290(CHEMBL483913 | Uridine-5'-methyl(C-P)-tetraphospha...)EC50: 4.18E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)
EC50: 3.95E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
EC50: 2.61E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
EC50: 1.45E+3nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
EC50: 870nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270548(CHEMBL454230 | Uridine-5'-(2'-deoxy-glucose)-6'-te...)
EC50: 4.32E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270547(CHEMBL508122 | Uridine-5'-mannose-6'-tetraphosphat...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270544(CHEMBL500840 | Uridine-5'-fructose-6'-tetraphospha...)
EC50: 6.30E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50205413(CHEMBL221326 | P(1),P(4)-bis(uridin-5'-yl) tetraph...)
EC50: 1.16E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
EC50: 270nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270548(CHEMBL454230 | Uridine-5'-(2'-deoxy-glucose)-6'-te...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270547(CHEMBL508122 | Uridine-5'-mannose-6'-tetraphosphat...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270543(CHEMBL448985 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
EC50: 4.78E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270542(CHEMBL474887 | Uridine-5'-cyclohexane-tetraphospha...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271292(CHEMBL482895 | Uridine-5'-alpha-glycerol-tetraphos...)
EC50: 1.12E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)
EC50: 1.96E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271290(CHEMBL483913 | Uridine-5'-methyl(C-P)-tetraphospha...)
EC50: 2.53E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)
EC50: 2.70E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
EC50: 4.64E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271224(2'-C-Methyl-uridine-5'-triphosphate | CHEMBL521487)
EC50: 1.26E+3nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270544(CHEMBL500840 | Uridine-5'-fructose-6'-tetraphospha...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270543(CHEMBL448985 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50270542(CHEMBL474887 | Uridine-5'-cyclohexane-tetraphospha...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271292(CHEMBL482895 | Uridine-5'-alpha-glycerol-tetraphos...)
EC50: 8.19E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271291(CHEMBL484105 | Uridine-5'-(2-cyanoethyl)-tetraphos...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271290(CHEMBL483913 | Uridine-5'-methyl(C-P)-tetraphospha...)
EC50: 8.16E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271289(CHEMBL519991 | Uridine-5'-methyl-tetraphosphate)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50271251(CHEMBL483502 | {[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-...)
EC50: 7.56E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50303341(Diphosphoric Acid 1-beta-Methyl Ester 2-(Uridine-5...)
BDBM50303332(Diphosphoric Acid 1-beta-(2-Cyanoethyl)Ester 2-(Ur...)EC50: 7.46E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303345(Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(Uridi...)EC50: 480nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303334(Diphosphoric Acid 1-r-Glycerol Ester 2-(Uridine-5'...)EC50: 1.60E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303335(Diphosphoric Acid 1-beta-Glycerol Ester 2-(Uridine...)EC50: 167nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303346(Diphosphoric Acid 1-beta-tert-Butyl Ester 2-(Uridi...)EC50: 252nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303336(Diphosphoric Acid 1-beta-Cyclohexyl Ester 2-(Uridi...)EC50: 5.16E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303341(Diphosphoric Acid 1-beta-Methyl Ester 2-(Uridine-5...)
BDBM50303332(Diphosphoric Acid 1-beta-(2-Cyanoethyl)Ester 2-(Ur...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50303334(Diphosphoric Acid 1-r-Glycerol Ester 2-(Uridine-5'...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50303335(Diphosphoric Acid 1-beta-Glycerol Ester 2-(Uridine...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50303336(Diphosphoric Acid 1-beta-Cyclohexyl Ester 2-(Uridi...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
BDBM50303351(triethylazanium ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)EC50: 8.00E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50303345(Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(Uridi...)
EC50: 1.52E+3nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50303346(Diphosphoric Acid 1-beta-tert-Butyl Ester 2-(Uridi...)
EC50: 1.08E+5nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells coexpressing phospholipase C-activating Gq protein assessed as [3H]inositol p...More data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 160nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50303351(triethylazanium ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
EC50: 4.58E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in HEK293 cells coexpressing phospholipase C-activating Gi protein cells assessed as inhibition of...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 80.4nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 3 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 59nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 4 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 100nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 500nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assayMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 73nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 49nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 90nMAssay Description:Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 60nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity as...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: >1.00E+5nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled human P2Y purinoceptor 11 (P2Y11)More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 6.00E+3nMAssay Description:The compound was evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 6 (P2Y6)More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 2.50E+3nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 2.60E+3nMAssay Description:The compound was evaluated for antagonist activity against phospholipase C coupled recombinant rat P2Y purinoceptor 4 (P2Y4)More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
EC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
EC50: 2.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
EC50: 9.80E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
EC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
EC50: >2.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
EC50: >1.00E+5nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 100nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
EC50: 2.20E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
EC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
EC50: 8.40E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
EC50: 200nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
EC50: >1.00E+5nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y4 ...More data for this Ligand-Target Pair
EC50: >1.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 90nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production by scintillation pr...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: 30nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
EC50: 5.60E+3nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y2 ...More data for this Ligand-Target Pair
EC50: >3.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
EC50: >1.00E+4nMAssay Description:Agonist activity evaluated as change in the level of cytosolic calcium in 1321N astrocytoma cells infected with a retrovirus encoding the human P2Y6 ...More data for this Ligand-Target Pair
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50341879(CHEMBL1767408 | Diquafosol)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
BDBM50241299(CHEMBL239151 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
BDBM50118213(5'-UTP | CHEMBL336296 | H4utp | UTP | uridine 5'-(...)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
BDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)
Kd: 1.50E+4nMAssay Description:Binding affinity to human Argonaut protein 2 PAZ domain assessed as dissociation constant by using isothermal titration microcalorimetryMore data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
EC50: 42nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
BDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)
EC50: 49nMAssay Description:Agonist activity at human P2Y6R expressed in 1321N1 cells assessed as calcium mobilization measured by microplate reader methodMore data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
Kd: 5.40E+4nMAssay Description:Inhibition of Klebsiella pneumoniae UGM expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50118239(CHEMBL130266 | UDP | Uridine diphosphate | uridine...)
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