Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University of Oxford

LigandBDBM26107((2R)-2-(formamidoformic acid)-3-phenylpropanoic ac...)Copy SMILESCopy InChI

Affinity DataIC50:  3.20E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseDrugBankMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
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TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM26107((2R)-2-(formamidoformic acid)-3-phenylpropanoic ac...)Copy SMILESCopy InChI

Affinity DataKd:  8.30E+4nMAssay Description:Inhibition of FIH (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseDrugBankMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI