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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Genome polyprotein
(Hepatitis C virus)
University Of Wollongong
Curated by
ChEMBL
Ligand
BDBM50126661
((2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-...)
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Affinity Data
Ki: 2.20E+3nM
Assay Description:
Inhibitory constant against hepatitis C virus NS3 protease
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
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Target
RNA-directed RNA polymerase
(Hepatitis C virus)
Shire Biochem
Curated by
ChEMBL
Ligand
BDBM50126666
(2-[(3-Cyano-benzyl)-(2,4-dichloro-benzoyl)-amino]-...)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RNA-directed RNA polymerase
(Hepatitis C virus)
Shire Biochem
Curated by
ChEMBL
Ligand
BDBM50126661
((2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-...)
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Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Genome polyprotein
(Hepatitis C virus (HCV))
Shire Biochem
Curated by
ChEMBL
Ligand
BDBM50139673
(2-[(2,4-Dichloro-benzoyl)-(3-trifluoromethyl-benzy...)
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Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of HCV NS5B polymerase
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
RNA-directed RNA polymerase
(Hepatitis C virus)
Shire Biochem
Curated by
ChEMBL
Ligand
BDBM50126668
((S)-2-(2,4-dichloro-N-(3-methylbenzyl)benzamido)-3...)
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Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RNA-directed RNA polymerase
(Hepatitis C virus)
Shire Biochem
Curated by
ChEMBL
Ligand
BDBM50126678
(2-[Benzyl-(2,4-dichloro-benzoyl)-amino]-3-phenyl-p...)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI