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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
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Target
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
(Homo sapiens (Human))
University Of North Carolina
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
Ki: 5.00E+6nM ΔG°: -13.7kJ/mole
pH: 5.8 T: 2°C
Assay Description:
Glycosylasparaginase activity was measured in citrate-phosphate buffer at pH 5.8 at 37 C. N-Acetyl-D-glucosamine released during the reaction was me...
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Target Info
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Target
Delta-aminolevulinic acid dehydratase
(Escherichia coli)
University Of NeuchÂTel
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
Ki: 1.25E+7nM ΔG°: -11.3kJ/mole
pH: 8.1 T: 2°C
Assay Description:
The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent).
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Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
IC50: 8.53E+4nM
Assay Description:
Inhibition of human PHD2 at 293K temperature by solvent relaxation technique
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Target Info
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Target
Lysine-specific demethylase 4E
(Homo sapiens (Human))
University Of Oxford
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
IC50: 7.10E+5nM
pH: 7.5 T: 2°C
Assay Description:
A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...
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Target
Prolyl 4-hydroxylase
(Paramecium bursaria Chlorella virus 1)
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/TrEMBL
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ChEBI
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Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
IC50: >1.00E+7nM
Assay Description:
Inhibition of PHD2 (unknown origin)
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Target Info
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Target
Methyl-accepting chemotaxis protein NahY
(Pseudomonas putida (Arthrobacter siderocapsulatus))
Csic
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
Kd: 8.20E+4nM
T: 2°C
Assay Description:
Measurements were done on a VP-microcalorimeter (MicroCal, Amherst, MA).
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Target Info
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ChEBI
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Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Affinity Data
Kd: >1.00E+5nM
Assay Description:
Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperature
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
MMDB
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Egl nine homolog 1
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM26121
(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
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Copy InChI
Affinity Data
Kd: >1.00E+5nM
Assay Description:
Binding affinity to human PHD2 by nondenaturing ESI-MS
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI