Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 50 hits in this display   

TargetLipopolysaccharide heptosyltransferase 1(Escherichia coli (strain K12))
Wesleyan University

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  2.80E+5nMAssay Description:Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  3.00E+5nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition constant against Alpha-FucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLipopolysaccharide heptosyltransferase 1(Escherichia coli (strain K12))
Wesleyan University

Curated by ChEMBL
LigandPNGBDBM228805(Galactose)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of glycogen phosphorylase b (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase-b after 1 min in presence of varying levels of glucose-1-phosphate and constant concentration of g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  1.70E+6nMpH: 6.8Assay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release using alphaD glucose-1-phosphate as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  1.70E+6nMAssay Description:Competitive inhibition of rabbit skeletal muscle glycogen phosphorylase b using Glc-1-P as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147883((S)-6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetra...)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibitory binding constant against glycogen phosphorylase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50102882(6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetraol |...)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibitory activity against muscle Glycogen Phosphorylase bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase inactive form bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  1.70E+6nMAssay Description:Inhibition of rabbit glycogen phosphorylase B enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50422217(CHEMBL2303800)
Affinity DataKi:  1.80E+6nMAssay Description:Inhibitory activity against rabbit muscle glycogen phosphorylaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  2.00E+6nMAssay Description:Competitive inhibition of rabbit muscle glycogen phosphorylase-a in presence of varying levels of glucose-1-phosphate and constant concentration of g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  2.77E+6nMAssay Description:Inhibitory activity against rabbit muscle glycogen phosphorylaseChecked by AuthorMore data for this Ligand-Target Pair
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University Of Tokyo

LigandPNGBDBM228805(Galactose)
Affinity DataKi:  4.14E+6nM ΔG°:  -14.1kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  4.28E+6nMAssay Description:Competitive inhibition of His6-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inorg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50351158(CHEMBL423707)
Affinity DataKi:  4.90E+6nMAssay Description:Inhibition of glycogen phosphorylase a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University Of Tokyo

LigandPNGBDBM228805(Galactose)
Affinity DataKi:  4.91E+6nM ΔG°:  -13.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University Of Tokyo

LigandPNGBDBM228805(Galactose)
Affinity DataKi:  5.61E+6nM ΔG°:  -13.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  6.70E+6nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  7.40E+6nMAssay Description:Inhibitory activity against muscle Glycogen Phosphorylase bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  7.40E+6nMAssay Description:Inhibitory binding constant against glycogen phosphorylase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
University Of Thessaly

Curated by ChEMBL
LigandPNGBDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Affinity DataKi:  7.40E+6nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase inactive form bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  7.94E+6nMAssay Description:Inhibitory activity against Pig Skeletal Glycogen Phosphorylase bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM34103(D-glucose | dextrose | glucose)
Affinity DataKi:  7.94E+6nMAssay Description:Inhibitory activity against Pig Skeletal Glycogen Phosphorylase bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50448403(CHEBI:4208 | D-Mannose)
Affinity DataKi:  1.31E+7nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50422217(CHEMBL2303800)
Affinity DataKi:  1.58E+7nMAssay Description:Inhibition of rabbit glycogen phosphorylase B enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50473924(CHEMBL134846)
Affinity DataKi:  1.58E+7nMAssay Description:Inhibitory activity against Pig Skeletal Glycogen Phosphorylase bMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, brain form(Homo sapiens (Human))
The University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147907((S)-2,6-Bis-hydroxymethyl-tetrahydro-pyran-2,3,4,5...)
Affinity DataKi:  1.58E+7nMAssay Description:Inhibitory binding constant against glycogen phosphorylase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  910nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50591453(CHEBI:42589 | CHEMBL1230861)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21 incubated for 24 hrs by fluorescence polarization based competitive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50591453(CHEBI:42589 | CHEMBL1230861)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB expressed in Escherichia coli BL21 (DE3) incubated for 6 hrs by Tecan-INFINITE F500 plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50448403(CHEBI:4208 | D-Mannose)
Affinity DataIC50:  5.20E+4nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50448403(CHEBI:4208 | D-Mannose)
Affinity DataIC50:  1.49E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50077229(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
Affinity DataIC50:  1.05E+6nMAssay Description:Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...More data for this Ligand-Target Pair
TargetC-type lectin domain family 4 member M(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50580865(CHEBI:42548 | CHEMBL1232862)
Affinity DataIC50:  2.48E+6nMAssay Description:Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.95E+6nMAssay Description:Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-type lectin domain family 4 member M(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50467903(CHEBI:28729 | CHEMBL365590)
Affinity DataIC50:  3.39E+6nMAssay Description:Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50467903(CHEBI:28729 | CHEMBL365590)
Affinity DataIC50:  6.40E+6nMAssay Description:Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN carbohydrate binding domain (unknown origin) expressed in Escheric...More data for this Ligand-Target Pair
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Affinity DataIC50: >3.00E+7nMAssay Description:Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalectin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataIC50:  5.00E+7nMAssay Description:Inhibition of recombinant galectin 1 in human O type red blood cells by hemagglutination assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalectin-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50423644(GALACTOSE)
Affinity DataIC50:  5.00E+7nMAssay Description:Inhibition of recombinant galectin 3 in human O type red blood cells by hemagglutination assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Affinity DataKd: >1.00E+7nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAsialoglycoprotein receptor 1(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50077229(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
Affinity DataKd:  1.46E+6nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
TargetType 1 fimbrin D-mannose specific adhesin(Escherichia coli (strain K12))
Indian Institute Of Technology Bombay

Curated by ChEMBL
LigandPNGBDBM50467903(CHEBI:28729 | CHEMBL365590)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to Escherichia coli FimH assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Indian Institute Of Technology Bombay

Curated by ChEMBL
LigandPNGBDBM228805(Galactose)
Affinity DataKd:  8.75E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA expressed in Escherichia coli assessed as dissociation constant by isothermal titration calorime...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetJacalin(Artocarpus heterophyllus)
University Of Delaware

Curated by ChEMBL
LigandPNGBDBM228805(Galactose)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to jackfruit jacalin by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed