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Found 6938 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112421(US8623889, 420)
Affinity DataKi:  0.0186nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112161(US8623889, 159)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112066(US8623889, 64)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112193(US8623889, 191)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112111(US8623889, 109)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50378812(CHEMBL1221411)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of recombinant c-Abl after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112312(US8623889, 311)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112230(US8623889, 228)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50303233(2-(3-aminophenylamino)-6-(2,6-dichlorophenyl)-8-me...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of recombinant c-Abl after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112359(US8623889, 358)
Affinity DataKi:  0.0200nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112099(US8623889, 97)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112029(US8623889, 27)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112251(US8623889, 249)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112105(US8623889, 103)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112289(US8623889, 287)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112274(US8623889, 272)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112275(US8623889, 273)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112288(US8623889, 286)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112106(US8623889, 104)
Affinity DataKi:  0.0300nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112144(US8623889, 142)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112192(US8623889, 190)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112252(US8623889, 250)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112032(US8623889, 30)
Affinity DataKi:  0.0400nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112244(US8623889, 242)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112255(US8623889, 253)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112245(US8623889, 243)
Affinity DataKi:  0.0500nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112078(US8623889, 76)
Affinity DataKi:  0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112254(US8623889, 252)
Affinity DataKi:  0.0600nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataKi:  0.0620nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112157(US8623889, 155)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112065(US8623889, 63)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112194(US8623889, 192)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112288(US8623889, 286)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112289(US8623889, 287)
Affinity DataKi:  0.0700nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112379(US8623889, 378)
Affinity DataKi:  0.0709nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112418(US8623889, 417)
Affinity DataKi:  0.0723nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112438(US8623889, 437)
Affinity DataKi:  0.0799nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112439(US8623889, 438)
Affinity DataKi:  0.0799nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112330(US8623889, 329)
Affinity DataKi:  0.0800nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112408(US8623889, 407)
Affinity DataKi:  0.0841nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112409(US8623889, 408)
Affinity DataKi:  0.0841nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112425(US8623889, 424)
Affinity DataKi:  0.0896nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112057(US8623889, 55)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112058(US8623889, 56)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112244(US8623889, 242)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112224(US8623889, 222)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112191(US8623889, 189)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112107(US8623889, 105)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112245(US8623889, 243)
Affinity DataKi:  0.0900nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM112156(US8623889, 154)
Affinity DataKi:  0.100nMAssay Description:Using the following procedure, varying concentration of compounds of the invention were assessed for their ability to inhibit c-Abl enzyme's phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
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