Found 611 Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase catalytic subunit alpha-1'
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of AMPKa1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full-length recombinant human GST and His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression system by LanthaScreen as...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant full length N-terminal GST/N-terminal His-tagged AMPK alpha1/beta1/gamma1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of AMPKalpha1beta1gamma1 (unknown origin) using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 173nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PRKKA1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 217nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 221nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 246nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 296nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 348nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 393nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 418nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 865nMAssay Description:Inhibition of AMPKa1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of AMPKalpha1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human full length AMPKalpha1 recombinant using AMARAASAAALAR as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of PRKAA1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant AMPKalpha1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of AMPK A1/B1/G1 by FRET assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of PRKKA1 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of AMPKA1More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Merck And
Curated by ChEMBL
Merck And
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of neuraminidase of influenza A/PR/8/34(H1N1)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataKd: 1.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataKd: 520nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair