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Found 105 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 5'
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataIC50:  7.20nMAssay Description:Antagonistic activity of the compound evaluated in adenylyl cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128187((1R,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128192((1S,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128210((1R,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128207((1S,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Rattus norvegicus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50140057(2-Hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetra...)
Affinity DataIC50:  2.80E+3nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128209((1R,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128203((1R,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Rattus norvegicus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50370376(CHEMBL1229920)
Affinity DataIC50:  4.60E+3nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128199((1S,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128188((1S,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128206((1S,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128191(2-[3-(6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydrox...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128205(2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyloxy]-N-h...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Rattus norvegicus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50025883((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymet...)
Affinity DataIC50:  1.50E+4nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119844(2-{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-N-...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128204((1R,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128202((1R,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128195((1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128197((1S,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128201((1S,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50: >7.00E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119853(2-{[(1S,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128190((1S,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...)
Affinity DataIC50:  7.32E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119860(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128186((1S,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119857(CHEMBL108067 | [(S)-3-((S)-6-Amino-purin-9-yl)-cyc...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119821(2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119821(2-[3-(6-Amino-purin-9-yl)-propoxy]-N-hydroxy-aceta...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119854(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119861(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  9.80E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128194((1R,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Rattus norvegicus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50008363(5-(6-Amino-2-fluoro-purin-9-yl)-2-hydroxymethyl-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128189((1S,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119854(2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119851(2-[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119829(CHEMBL104969 | [3-(6-Amino-purin-9-yl)-propoxy]-ac...)
Affinity DataIC50:  1.41E+5nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128211((1S,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50:  1.88E+5nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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