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Found 172 Enz. Inhib. hit(s) with Target = 'Alpha-galactosidase'
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50260444(CHEMBL4073111)
Affinity DataKi:  8nMAssay Description:Competitive inhibition of coffee beans alpha-galactosidase pre-incubated for 1 hr followed by p-nitrophenyl-alpha-D-galactopyranoside substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  13nMAssay Description:Inhibition of alpha-galactosidase green coffee beansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50260443(CHEMBL4096086)
Affinity DataKi:  62nMAssay Description:Competitive inhibition of coffee beans alpha-galactosidase pre-incubated for 1 hr followed by p-nitrophenyl-alpha-D-galactopyranoside substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564233(CHEMBL4792854)
Affinity DataKi:  200nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human lysosome alpha-galactosidase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50321618(CHEMBL1172470 | N-(N'-Biotinylaminoethyl)-aminocar...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of alpha-galactosidase green coffee beansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564237(CHEMBL4793095)
Affinity DataKi:  1.50E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50182795(5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of green coffee bean alpha-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50375511(CHEMBL406973)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using o-nitrophenyl alpha-D-galactopyranoside after 10 to 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50234559(CHEMBL4081664)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of recombinant human alpha GAL-A using varying levels of 4-methylumbelliferyl alpha-D-galactopyranoside substrate at pH 7 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50520994(CHEMBL4529797)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of green coffee bean alpha-galactosidaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50356096(CHEMBL1911831)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of green coffee bean alpha-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50290908(CHEMBL4160428)
Affinity DataKi:  3.50E+3nMAssay Description:Competitive inhibition of human recombinant alpha-galactosidase A using 4-MU-alpha-d-galactopyranoside as substrate by Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564249(CHEMBL4789325)
Affinity DataKi:  3.70E+3nMAssay Description:Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564236(CHEMBL4782789)
Affinity DataKi:  7.40E+3nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50234559(CHEMBL4081664)
Affinity DataKi:  7.70E+3nMAssay Description:Non-competitive inhibition of recombinant human alpha GAL-A using varying levels of 4-methylumbelliferyl alpha-D-galactopyranoside substrate at pH 4....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564235(CHEMBL4793871)
Affinity DataKi:  1.80E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  1.80E+4nMAssay Description:Compound tested for inhibition of alpha-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564251(CHEMBL4781544)
Affinity DataKi:  3.20E+4nMAssay Description:Non-competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50437446(CHEMBL2409341)
Affinity DataKi:  5.40E+4nMAssay Description:Inhibition of coffee bean alpha-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50287006(Azepane-3,4,5,6-tetraol | CHEMBL13922)
Affinity DataKi:  6.70E+4nMAssay Description:Compound was tested for inhibition of alpha-galactosidase from green coffee beans.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50456585(CHEMBL4218664)
Affinity DataKi:  7.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50236280(CHEMBL4100971)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50185229((2R,3S,4R,6R)-6-heptyl-2-(hydroxymethyl)piperidine...)
Affinity DataKi:  1.41E+5nMAssay Description:Inhibition of green coffee alpha galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50137351(2-(R)-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyr...)
Affinity DataKi:  3.00E+5nMAssay Description:Compound tested for inhibition of alpha-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50260445(CHEMBL4064761)
Affinity DataKi:  3.64E+5nMAssay Description:Inhibition of coffee beans alpha-galactosidase pre-incubated for 1 hr followed by p-nitrophenyl-alpha-D-galactopyranoside substrate addition by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50137350(2-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2...)
Affinity DataKi:  4.00E+5nMAssay Description:Compound tested for inhibition of alpha-galactosidase from Aspergillus nigerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50185230((2R,3S,4R,6R)-6-ethyl-2-(hydroxymethyl)piperidine-...)
Affinity DataKi:  7.21E+5nMAssay Description:Inhibition of green coffee alpha galactosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50186735(CHEMBL208021 | D-1,4-dideoxy-4,4-difluoromannonoji...)
Affinity DataKi: >1.00E+6nMpH: 6.8Assay Description:Inhibition of green coffee beans alpha galactosidase at pH 6.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50186736(CHEMBL380311 | L-1,4-dideoxy-4,4-difluorogulonojir...)
Affinity DataKi: >1.00E+6nMpH: 6.8Assay Description:Inhibition of green coffee beans alpha galactosidase at pH 6.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50186733(CHEMBL208152 | L-1,4,6-trideoxy-4,4-difluoronojiri...)
Affinity DataKi: >1.00E+6nMpH: 6.8Assay Description:Inhibition of green coffee beans alpha galactosidase at pH 6.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50186734(CHEMBL207910 | D-1,4-dideoxy-4,4-difluoronojirimyc...)
Affinity DataKi: >1.00E+6nMpH: 6.8Assay Description:Inhibition of green coffee beans alpha galactosidase at pH 6.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica)
Université

Curated by ChEMBL
LigandPNGBDBM50186732(CHEMBL206628 | D-1,4,6-trideoxy-4,4-difluoronojiri...)
Affinity DataKi: >1.00E+6nMpH: 6.8Assay Description:Inhibition of green coffee beans alpha galactosidase at pH 6.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50150471(CHEMBL3770764)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50150472(CHEMBL3770736)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50350758(CHEMBL1818433)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50150470(CHEMBL3771185)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human recombinant lysosomal alpha-galactosidase using 2,4-dinitrophenyl-alpha-D-galactopyranoside as substrate preincubated up to 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113762(1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...)
Affinity DataIC50:  0.780nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113758(DGJ-pMe SPhT)
Affinity DataIC50:  1.40nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  3nMpH: 6.5Assay Description:Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113762(1-Deoxygalactonojirimycin (DGJ) | 2-(hydroxymethyl...)
Affinity DataIC50:  3nMpH: 5.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113758(DGJ-pMe SPhT)
Affinity DataIC50:  8.30nMpH: 5.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...More data for this Ligand-Target Pair
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50260444(CHEMBL4073111)
Affinity DataIC50:  16nMAssay Description:Competitive inhibition of coffee beans alpha-galactosidase pre-incubated for 1 hr followed by p-nitrophenyl-alpha-D-galactopyranoside substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113757(DGJ-pMe OPhT)
Affinity DataIC50:  16nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...More data for this Ligand-Target Pair
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM113759(DGJ-pF PhT)
Affinity DataIC50:  43nMpH: 7.0Assay Description:For inhibition assay, 0.1% Triton X-100 extracts were mixed with 4-MU substrates ( 5 mM 4-MU α-ᴅ-galactopyranoside and 0.1 M N-acetyl-J...More data for this Ligand-Target Pair
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50099009((3S,4S,5R)-2-Aminomethyl-5-hydroxymethyl-pyrrolidi...)
Affinity DataIC50:  53nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysisMore data for this Ligand-Target Pair
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