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Found 48 Enz. Inhib. hit(s) with Target = 'Amiloride-sensitive sodium channel subunit alpha'
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112167(CHEMBL3608428)
Affinity DataIC50:  6nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112170(CHEMBL3608425)
Affinity DataIC50:  6nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190466(CHEMBL212431 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190487(CHEMBL212531 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190462(CHEMBL212432 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  8nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112171(CHEMBL3608426)
Affinity DataIC50:  9nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190486(CHEMBL211161 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190494(CHEMBL209303 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  9nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112172(CHEMBL3608427)
Affinity DataIC50:  13nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190481(CHEMBL214239 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  14nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190459(CHEMBL377986 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  15nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190484(CHEMBL210876 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190468(CHEMBL211600 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  17nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190475(CHEMBL380011 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190489((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112169(CHEMBL3608424)
Affinity DataIC50:  20nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190458(CHEMBL386222 | sulfuric acid mono-(4-{4-[N-(3,5-di...)
Affinity DataIC50:  21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190465(1-(4-(4-aminophenyl)butyl)-3-(3,5-diamino-2-chloro...)
Affinity DataIC50:  21nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190488(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190480(CHEMBL214220 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  25nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190490(CHEMBL212534 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  26nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190493(CHEMBL211658 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  28nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190456(CHEMBL209659 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  29nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190471(CHEMBL379066 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  30nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190455(CHEMBL208889 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  31nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190478(CHEMBL211946 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  32nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190460(CHEMBL211773 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  41nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190457(CHEMBL211072 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  42nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190483((4-{4-[N-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50:  48nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190479(CHEMBL211664 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  50nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190477(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbonyl)...)
Affinity DataIC50:  51nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190461(CHEMBL208620 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  58nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190463(CHEMBL209977 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  62nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190464(1-(3,5-diamino-2-chloropyrazine-6-carbonyl)-3-(5-(...)
Affinity DataIC50:  64nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190485(CHEMBL211611 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM81819(Benzamil | CAS_1937-37-7 | CHEMBL212579 | NSC_1081...)
Affinity DataIC50:  66nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190470(CHEMBL377239 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  68nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Mus musculus)
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50112168(CHEMBL3608423)
Affinity DataIC50:  70nMAssay Description:Inhibition of ENaC in mouse M1 assessed as effect on trans epithelial electrical resistance by measuring short circuit currents by voltage-clamp base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190474(6-(4-{4-[N'-(3,5-diamino-6-chloropyrazine-2-carbon...)
Affinity DataIC50:  73nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190495(CHEMBL209104 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  77nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190491(CHEMBL210966 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  87nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190472(CHEMBL211793 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  88nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190473(CHEMBL377688 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  107nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190492(CHEMBL210981 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  108nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190482(CHEMBL210967 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  124nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM115076(3,5-bis(azanyl)-N-[azanyl(phenylazanyl)methylidene...)
Affinity DataIC50:  401nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190469(CHEMBL210866 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  477nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)
Affinity DataIC50:  776nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed