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Found 42 Enz. Inhib. hit(s) with Target = 'Sodium- and chloride-dependent creatine transporter 1'
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143301((2-Hydroxy-ethyl)-dimethyl-octyl-ammonium | CHEMBL...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [3H]choline brain uptake through choline transporter was determined in situ brain perfusion studies in Male Fischer-344 ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143312(CHEMBL53882 | Hexyl-(2-hydroxy-ethyl)-dimethyl-amm...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143301((2-Hydroxy-ethyl)-dimethyl-octyl-ammonium | CHEMBL...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143312(CHEMBL53882 | Hexyl-(2-hydroxy-ethyl)-dimethyl-amm...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50060526(2-Dimethylamino-ethanol | 2-hydroxy-N,N-dimethylet...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of [3H]choline brain uptake through choline transporter was determined in situ brain perfusion studies in Male Fischer-344 ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50119791(1-Decyl-3-((S)-1-methyl-pyrrolidin-2-yl)-pyridiniu...)
Affinity DataKi:  2.70E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147117(1-Octyl-piperidine | CHEMBL105218)
Affinity DataKi:  3.20E+4nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147114(Butyl-(2-hydroxy-ethyl)-dimethyl-ammonium | CHEMBL...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50026220(2-hydroxy-N,N,N-trimethylethanaminium | CHEMBL2824...)
Affinity DataKi:  4.20E+4nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147104(3-(1-Methyl-pyrrolidin-2-yl)-1-octyl-piperidine | ...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50119801((S)-3-(1-methylpyrrolidin-2-yl)-1-octylpyridinium ...)
Affinity DataKi:  4.90E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50048111((2,3-Dihydroxy-phenyl)-trimethyl-ammonium; iodide ...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition of high affinity dopamine uptake at concentration of 1 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147116(CHEMBL105536 | Ethyl-(2-hydroxy-ethyl)-dimethyl-am...)
Affinity DataKi:  9.40E+4nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147122(2-(Dimethyl-lambda*4*-sulfanyl)-ethanol | CHEMBL54...)
Affinity DataKi:  1.17E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147120(2-Methylamino-ethanol | 2-hydroxy-N-methylethanami...)
Affinity DataKi:  1.27E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50048110(CHEMBL57055 | [2-(3,4-Dihydroxy-phenyl)-2-hydroxy-...)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition constant of high-affinity 5-HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147119((3-Hydroxy-propyl)-trimethyl-ammonium | CHEMBL1209...)
Affinity DataKi:  1.62E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147103((2-Hydroxy-ethyl)-dimethyl-propyl-ammonium | CHEMB...)
Affinity DataKi:  1.90E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147112(2-hydroxy-N,N,N-trimethylpropanaminium | 2-methylc...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50047005(1-Aza-bicyclo[2.2.2]octan-3-ol | 1-Aza-bicyclo[2.2...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143296(1-Butyl-pyridinium | CHEMBL443525)
Affinity DataKi:  2.50E+5nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50143295(1-Octyl-pyridinium; iodide | 1-octylpyridinium iod...)
Affinity DataKi:  2.50E+5nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147108(2-Hydroxy-4,4-dimethyl-2-phenyl-morpholin-4-ium | ...)
Affinity DataKi:  3.84E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147124(1-(4-Phenethyl-cyclohex-1-enyl)-ethanone | CHEMBL1...)
Affinity DataKi:  4.95E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147118((2-Hydroxy-cyclohexyl)-trimethyl-ammonium | CHEMBL...)
Affinity DataKi:  5.74E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147100((4-Fluoro-phenyl)-(2-hydroxy-ethyl)-dimethyl-ammon...)
Affinity DataKi:  7.37E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM7973(2-aminoethan-1-ol | CHEMBL104943 | ethanolamine)
Affinity DataKi:  9.03E+5nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50366913(CHEMBL555023)
Affinity DataKi:  1.90E+6nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147110(CHEMBL104897 | Ethyl-trimethyl-ammonium)
Affinity DataKi:  4.70E+6nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147123(((1R,2S)-2-Hydroxy-cyclohexyl)-trimethyl-ammonium ...)
Affinity DataKi:  5.37E+6nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147102(1-Methylpyridinium | CHEMBL302326 | N-methylpyridi...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147101(1-(1-Ethyl-1,2,3,6-tetrahydro-pyridin-4-yl)-ethano...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147105((4-Hydroxy-butyl)-trimethyl-ammonium | CHEMBL10228...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147109(1-Methyl-3-(1-methyl-pyrrolidin-2-yl)-piperidine |...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147115(((1R,2R)-2-Hydroxy-cyclohexyl)-trimethyl-ammonium ...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147106(2-Dimethylamino-cyclohexanol | CHEMBL103052)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147111((2-Hydroxy-ethyl)-dimethyl-phenyl-ammonium | CHEMB...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147113((2-Hydroxy-1-methyl-ethyl)-trimethyl-ammonium | CH...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50026479(2-Methylsulfanyl-ethanol | CHEMBL277871)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50147121(3-(4-Pyridin-3-ylmethyl-piperazin-1-yl)-propan-1-o...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of [3H]-choline brain uptake was determined by in situ brain perfusion studies in male ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50048111((2,3-Dihydroxy-phenyl)-trimethyl-ammonium; iodide ...)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of high affinity choline uptake at concentration of 1 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50048110(CHEMBL57055 | [2-(3,4-Dihydroxy-phenyl)-2-hydroxy-...)
Affinity DataIC50:  2.21E+5nMAssay Description:Inhibition of high affinity choline uptake at concentration of 1 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed