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Found 3509 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617046(US11752155, Compound E1-38.6B')
Affinity DataKi:  0.110nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617044(US11752155, Compound E1-38.2B')
Affinity DataKi:  0.180nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617051(US11752155, Compound III-E1-38.1B')
Affinity DataKi:  0.290nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617045(US11752155, Compound E1-38.4B')
Affinity DataKi:  0.350nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM388301(US10294230, Compound E1-22.2 | US10584127, Compoun...)
Affinity DataKi:  0.413nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617024(US11752155, Compound E1-22.5B')
Affinity DataKi:  0.490nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124914(CHEMBL161180 | N-(3,5-Dichloro-benzyl)-4-trifluoro...)
Affinity DataKi:  0.600nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124885((E)-N-(2-Methoxy-benzyl)-3-phenyl-acrylamidine | C...)
Affinity DataKi:  0.700nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM388302(US10294230, Compound E1-21.2 | US10584127, Compoun...)
Affinity DataKi:  0.716nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617047(US11752155, Compound E1-38.8B')
Affinity DataKi:  0.800nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617030(US11752155, Compound E1-22.3B')
Affinity DataKi:  0.810nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287603(BDBM393497 | BDBM413611 | BDBM617007 | US9567341, ...)
Affinity DataKi:  0.838nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617032(US11752155, Compound E1-22.6B')
Affinity DataKi:  0.940nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM388303(US10294230, Compound E1-21.26 | US10584127, Compou...)
Affinity DataKi:  1.02nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617055(US11752155, Compound E2-38.2B')
Affinity DataKi:  1.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617031(US11752155, Compound E1-22.4B')
Affinity DataKi:  1.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124909(CHEMBL159744 | N-(3,5-Dimethyl-benzyl)-4-trifluoro...)
Affinity DataKi:  1.20nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617026(US11752155, Compound E1-21.4B')
Affinity DataKi:  1.30nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617034(US11752155, Compound E1-23.2B')
Affinity DataKi:  1.30nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198694(US9221796, 23b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM435146(US10584127, Compound E1-8.2 | US11136328, Compound...)
Affinity DataKi:  1.40nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198665(US9221796, 2b)
Affinity DataKi:  1.40nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198694(US9221796, 23b)
Affinity DataKi:  1.40nM ΔG°:  -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198665(US9221796, 2b)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287602(US10420768, Compound C-178 | US11752155, Compound ...)
Affinity DataKi:  1.42nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198687(US9221796, 18b)
Affinity DataKi:  1.5nM ΔG°:  -54.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617049(US11752155, Compound III-E1-22.1B')
Affinity DataKi:  1.5nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198681(US9221796, 13b)
Affinity DataKi:  1.60nM ΔG°:  -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617033(US11752155, Compound E1-22.28B')
Affinity DataKi:  1.60nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198685(US9221796, 17)
Affinity DataKi:  1.60nM ΔG°:  -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499215(CHEMBL3735947)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499215(CHEMBL3735947)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198835(US9221796, 116)
Affinity DataKi:  2nM ΔG°:  -53.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212688(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Affinity DataKi:  2nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM50124908(CHEMBL159560 | N-(2-Methoxy-benzyl)-4-trifluoromet...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat GluN2B receptor after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617038(US11752155, Compound E1-24.2B')
Affinity DataKi:  2.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50539161(CHEMBL4637295)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212685(2-benzofuran-7-ylmethyl-5-trifluoromethoxy-2,3-dih...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50037706(CHEMBL3357791)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]ifenprodil from human GluN2B expressed in mouse L(tk-) cells co-expressing GluN1a after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617041(US11752155, Compound E1-37.2B')
Affinity DataKi:  2.40nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198724(US9221796, 45, P-4)
Affinity DataKi:  2.5nM ΔG°:  -53.2kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617021(US11752155, Compound E1-1.5B')
Affinity DataKi:  2.55nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617025(US11752155, Compound E1-22.30B')
Affinity DataKi:  2.60nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198834(US9221796, 115)
Affinity DataKi:  2.70nM ΔG°:  -53.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-1 | US10501451, Example 2...)
Affinity DataKi:  2.79nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-1 | US10501451, Example 2...)
Affinity DataKi:  2.79nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-1 | US10501451, Example ...)
Affinity DataKi:  2.80nMAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 μg/well). The experimental co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-1 | US10501451, Example ...)
Affinity DataKi:  2.80nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM617050(US11752155, Compound III-E1-37.1B')
Affinity DataKi:  2.90nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM198692(US9221796, 22)
Affinity DataKi:  2.90nM ΔG°:  -52.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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