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Found 8 Enz. Inhib. hit(s) with Target = 'Sterol 26-hydroxylase, mitochondrial'
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326835(2-(2-Bromobenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  59nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50556038(CHEMBL389014)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP27A1 (unknown origin) expressed in Chinese hamster V79 cells using 1alpha-(OH)D3 as substrate measured after 24 hrs by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50214607(CHEMBL541423 | MK-24 | MK-24(S)-S(O)(NH)Ph)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CYP27A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP27A1 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50155468(2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326833(2-(2-Trifluoromethylbenzyl)-6-methoxy-tetralone | ...)
Affinity DataIC50:  5.34E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326832((E)-2-(2-(E)-Styrylbenzylidene)-6-methoxy-tetralon...)
Affinity DataIC50:  5.69E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 26-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50326834(2-(2-Ethylbenzyl)-6-methoxy-tetralone | CHEMBL1253...)
Affinity DataIC50:  8.23E+3nMAssay Description:Inhibition of CYP27A1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed