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Found 67 Enz. Inhib. hit(s) with Target = 'Alpha-amylase'
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120853(CHEMBL3618492)
Affinity DataKi:  190nMAssay Description:Non-competitive inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataKi:  340nMAssay Description:Competitive inhibition of Bacillus stearothermophilus alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120849(CHEMBL3618490)
Affinity DataKi:  700nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-Pgg | 1,2,3,4,6-pentakis-O-(3,4,5-trihyd...)
Affinity DataKi:  2.60E+3nMAssay Description:Non-competitive inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50339930(CHEMBL1761668 | N1-((S)-1-((S)-1-amino-3-(4-hydrox...)
Affinity DataKi:  1.10E+5nMAssay Description:Competitive inhibition of Bacillus stearothermophilus alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50339929(CHEMBL1761667 | N1-((S)-1-((S)-1-amino-3-(4-hydrox...)
Affinity DataKi:  1.40E+6nMAssay Description:Competitive inhibition of Bacillus stearothermophilus alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase type A isozyme(Hordeum vulgare)
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120841(CHEMBL3616593)
Affinity DataKi: <1.00E+7nMAssay Description:Inhibition of recombinant barley alpha-amylase isozyme-1 using DP17 amylose as substrate preincubated for 5 mins followed by substrate addition by co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataIC50:  34nMpH: 7.0Assay Description:After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  996nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50231670((2R,3R,4R,5S)-1-(8-(3-(3H-1,2,3-triazol-4-yl)pheno...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of alpha glucosidase from bacillus sterothermophilusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of alpha glucosidase from bacillus sterothermophilusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-Pgg | 1,2,3,4,6-pentakis-O-(3,4,5-trihyd...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate assessed as CNP liberation by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50231671((2R,3R,4R,5S)-1-(6-(3-(3H-1,2,3-triazol-4-yl)pheno...)
Affinity DataIC50:  2.41E+3nMAssay Description:Inhibition of alpha glucosidase from bacillus sterothermophilusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Tenebrio molitor)
Nanyang Technological University

Curated by ChEMBL
LigandPNGBDBM50090176(CHEMBL3581562)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Tenebrio molitor alpha-amylase pre-incubated for 20 mins at 37 degC by bernfeld methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Acarus siro (Flour mite))
Academy Of Sciences Of The Czech Republic

LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  3.80E+3nMpH: 4.5Assay Description:α-Amylase activity was assayed with the chromogenic substrate RBB-starch. An enzyme aliquot was incubated (20 min, 26°C) with 0.3% RBB-starch in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus stearothermophilus)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50231672((2R,3R,4R,5S)-1-(4-(3-(1H-1,2,3-triazol-4-yl)pheno...)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of alpha glucosidase from bacillus sterothermophilusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  9.64E+3nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  1.02E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174833(CHEMBL199442 | N-(3-(3-(3,4-dihydroxyphenyl)acrylo...)
Affinity DataIC50:  1.68E+4nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  1.84E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  1.96E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  2.14E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  3.02E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  3.73E+4nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120845(CHEMBL3618485)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus subtilis (strain 168))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50499987(CHEMBL3742315)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of Bacillus subtilis alpha-amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM23412(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H...)
Affinity DataIC50:  4.80E+4nMpH: 6.0 T: 2°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120834(CHEMBL2011396)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120835(CHEMBL2011401)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174835(4'-(4-toluenesulfonamido)-4-hydroxychalcone | 4'-(...)
Affinity DataIC50:  8.78E+4nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120832(CHEMBL3618483)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120831(CHEMBL3618482)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50293578(4-(2-(4-Hydroxyphenylamino)thiazol-4-yl)benzene-1,...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50293573(4-(4-(2,4-dihydroxyphenyl)thiazol-2-ylamino)benzen...)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174837(4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120823(CHEMBL1904421)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120836(CHEMBL572150)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174839(1-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-o...)
Affinity DataIC50:  2.69E+5nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120846(CHEMBL3618486)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120824(CHEMBL3618478)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120826(CHEMBL1510984)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120830(CHEMBL599385)
Affinity DataIC50:  4.23E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50293577(4-(4-(4-Hydroxyphenyl)thiazol-2-ylamino)phenol | C...)
Affinity DataIC50:  4.92E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120829(CHEMBL596726)
Affinity DataIC50:  6.42E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120828(CHEMBL590969)
Affinity DataIC50:  6.80E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120837(CHEMBL3618484)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50051863(CHEMBL1081479)
Affinity DataIC50:  7.35E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120827(CHEMBL3618481)
Affinity DataIC50:  8.50E+5nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
Freie Universit£t Berlin

Curated by ChEMBL
LigandPNGBDBM50120825(CHEMBL3618480)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of human salivary alpha-amylase using GalG2CNP as substrate by UV-Vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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