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Found 325 Enz. Inhib. hit(s) with Target = 'Protein-lysine 6-oxidase'
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526737(CHEMBL4528500 | US10807974, Example 82 | US1099508...)
Affinity DataIC50: <180nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Mus musculus)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526737(CHEMBL4528500 | US10807974, Example 82 | US1099508...)
Affinity DataIC50: <180nMAssay Description:To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526721(CHEMBL4444163 | US10807974, Example 111 | US109950...)
Affinity DataIC50:  190nMAssay Description:Cell Culture and TransfectionAll cell lines used in this study was purchased from American Type Culture Collection (ATCC). Mycoplasma contamination w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Mus musculus)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50526721(CHEMBL4444163 | US10807974, Example 111 | US109950...)
Affinity DataIC50:  190nMAssay Description:To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469007(US10807974, Example 16 | US10995088, Example 16 | ...)
Affinity DataIC50:  300nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469007(US10807974, Example 16 | US10995088, Example 16 | ...)
Affinity DataIC50:  300nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633180(4-((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-2-methyl...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633181(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(N,N-di...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633197(N,N′-((((((((((5-(1-((Z)-4-amino-2-fluorobut...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633202(N,N′-((((5-(1-((Z)-4-amino-2-fluorobut-2-en-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633203(5-(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(N,N...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633204(5-(4-(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633224(4-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633227(2-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633233(3-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633244(3-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633245((3aS,4S,6aR)-4-(5-(4-(3-(3-(((Z)-4-amino-2-fluorob...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633246((3aS,3a'S,4S,4'S,6aR,6a′R)-4,4′-(((((5...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633247((3aS,3a'S,4S,4'S,6aR,6a′R)-4,4′-(((((3...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633248((3aS,4S,6aR)-4-(4-(4-(3-((3-(((Z)-4-amino-2-fluoro...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633249(N-((1-(4-(((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-...)
Affinity DataIC50: <300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM633250(N-((1-(4-(((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-...)
Affinity DataIC50: >300nMAssay Description:The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the isoenz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469005(US10807974, Example 9 | US10995088, Example 9 | US...)
Affinity DataIC50:  340nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469005(US10807974, Example 9 | US10995088, Example 9 | US...)
Affinity DataIC50:  340nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM50505633(CHEMBL4448713)
Affinity DataIC50:  398nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM50505649(CHEMBL4439437)
Affinity DataIC50:  398nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469011(US10807974, Example 27 | US10995088, Example 27 | ...)
Affinity DataIC50:  400nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469011(US10807974, Example 27 | US10995088, Example 27 | ...)
Affinity DataIC50:  400nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469032(US10807974, Example 43 | US10995088, Example 43 | ...)
Affinity DataIC50:  420nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469032(US10807974, Example 43 | US10995088, Example 43 | ...)
Affinity DataIC50:  420nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469023(US10807974, Example 39 | US10995088, Example 39 | ...)
Affinity DataIC50:  440nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469023(US10807974, Example 39 | US10995088, Example 39 | ...)
Affinity DataIC50:  440nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469008(US10807974, Example 17 | US10995088, Example 17 | ...)
Affinity DataIC50:  450nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469019(US10807974, Example 35 | US10995088, Example 35 | ...)
Affinity DataIC50:  450nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469008(US10807974, Example 17 | US10995088, Example 17 | ...)
Affinity DataIC50:  450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469019(US10807974, Example 35 | US10995088, Example 35 | ...)
Affinity DataIC50:  450nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469024(US10807974, Example 40 | US10995088, Example 40 | ...)
Affinity DataIC50:  470nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469024(US10807974, Example 40 | US10995088, Example 40 | ...)
Affinity DataIC50:  470nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469004(US10807974, Example 5 | US10995088, Example 5 | US...)
Affinity DataIC50:  480nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469004(US10807974, Example 5 | US10995088, Example 5 | US...)
Affinity DataIC50:  480nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM50505657(CHEMBL4467234)
Affinity DataIC50:  501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM50505659(CHEMBL4459524)
Affinity DataIC50:  501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

US Patent
LigandPNGBDBM50505655(CHEMBL4441299)
Affinity DataIC50:  501nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469027(US10807974, Example 12 | US10995088, Example 12 | ...)
Affinity DataIC50:  510nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469027(US10807974, Example 12 | US10995088, Example 12 | ...)
Affinity DataIC50:  510nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Sus scrofa)
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469018(US10807974, Example 34 | US10995088, Example 34 | ...)
Affinity DataIC50:  530nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469018(US10807974, Example 34 | US10995088, Example 34 | ...)
Affinity DataIC50:  530nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50:  550nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
The Institute Of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM469010(US10807974, Example 26 | US10995088, Example 26 | ...)
Affinity DataIC50:  550nMAssay Description:The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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