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Found 451 Enz. Inhib. hit(s) with Target = 'Aryl hydrocarbon receptor'
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23936(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  0.200nM ΔG°:  -51.5kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23929(1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benz...)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23937(1,3-dichloro-5-[(E)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  1.40nM ΔG°:  -47.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23932(1,3-bis(trifluoromethyl)-5-[(E)-2-[4-(trifluoromet...)
Affinity DataKi:  2.10nM ΔG°:  -46.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23933(1-[(E)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  3.10nM ΔG°:  -45.1kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23931(1,3-difluoro-5-[(E)-2-(4-fluorophenyl)ethenyl]benz...)
Affinity DataKi:  3.80nM ΔG°:  -44.7kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23934(1-[(E)-2-(4-ethoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  5nM ΔG°:  -44.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23939(1,3-dichloro-5-[(E)-2-(3-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  5.70nM ΔG°:  -43.7kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23938(1,3-dichloro-5-[(E)-2-[3-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  6.80nM ΔG°:  -43.3kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50240990(2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23928(1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  7.70nM ΔG°:  -43.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23930(1,3-difluoro-5-[(E)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  9.20nM ΔG°:  -42.6kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23947(1-[(Z)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23946(1-[(Z)-2-(4-ethoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23949(1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23941(1,3-dichloro-5-[(Z)-2-(4-chlorophenyl)ethenyl]benz...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23949(1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23946(1-[(Z)-2-(4-ethoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23941(1,3-dichloro-5-[(Z)-2-(4-chlorophenyl)ethenyl]benz...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23949(1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  12nM ΔG°:  -42.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23947(1-[(Z)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  12nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23941(1,3-dichloro-5-[(Z)-2-(4-chlorophenyl)ethenyl]benz...)
Affinity DataKi:  13nM ΔG°:  -41.8kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23948(1,3-dichloro-5-[(Z)-2-[4-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  14nM ΔG°:  -41.7kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23950(1,3-dichloro-5-[(Z)-2-[3-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  19nM ΔG°:  -41.0kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23935(1-[(E)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  20nM ΔG°:  -40.8kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23942(1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  22nM ΔG°:  -40.6kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23951(1,3-dichloro-5-[(Z)-2-(3-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  24nM ΔG°:  -40.4kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23947(1-[(Z)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  43nM ΔG°:  -39.1kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23944(1,3-bis(trifluoromethyl)-5-[(Z)-2-[4-(trifluoromet...)
Affinity DataKi:  60nM ΔG°:  -38.3kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23943(1,3-difluoro-5-[(Z)-2-(4-fluorophenyl)ethenyl]benz...)
Affinity DataKi:  63nM ΔG°:  -38.2kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23946(1-[(Z)-2-(4-ethoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  65nM ΔG°:  -38.1kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  75nM ΔG°:  -37.8kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50605060(CHEMBL5198290)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23945(1-[(Z)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  96nM ΔG°:  -37.2kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Oryctolagus cuniculus (rabbit))
Institut Claudius Regaud

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataKi:  169nM ΔG°:  -35.9kJ/molepH: 7.6 T: 2°CAssay Description:Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
Palack£

Curated by ChEMBL
LigandPNGBDBM50605061(CHEMBL5179114)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50506041(CHEBI:16946 | L-kynurenine)
Affinity DataKi:  2.16E+4nMAssay Description:Inhibition of AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23945(1-[(Z)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  1.04E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23940(1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]be...)
Affinity DataKi:  1.33E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23946(1-[(Z)-2-(4-ethoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  1.54E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23943(1,3-difluoro-5-[(Z)-2-(4-fluorophenyl)ethenyl]benz...)
Affinity DataKi:  1.59E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23944(1,3-bis(trifluoromethyl)-5-[(Z)-2-[4-(trifluoromet...)
Affinity DataKi:  1.67E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23947(1-[(Z)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  2.33E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23951(1,3-dichloro-5-[(Z)-2-(3-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  4.17E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23942(1,3-difluoro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...)
Affinity DataKi:  4.55E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23935(1-[(E)-2-(4-butoxyphenyl)ethenyl]-3,5-dimethoxyben...)
Affinity DataKi:  5.01E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM23950(1,3-dichloro-5-[(Z)-2-[3-(trifluoromethyl)phenyl]e...)
Affinity DataKi:  5.27E+7nMAssay Description:Binding affinity to aryl hydrocarbon receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
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