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Found 14 Enz. Inhib. hit(s) with Target = 'DNA-3-methyladenine glycosylase'
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488844(3-BENZYLADENINE)
Affinity DataIC50:  400nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488842(3-BUTYLADENINE)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488843(3-PROPYLADENINE)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human purified MPG binding to immobilized ethenoadenine containing 5'-TCGAGGATCCTGAGCTCGAGTCGACGXTCGCGAATTCTGCGGATCCAAGC-3' duplex olig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488845(3-ETHYLADENINE)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of MPG in human A549 cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50559764(CHEMBL4751946)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of human AAG using HXO2/Loop01 oligonucleotide as substrate incubated for 2 hrs by colorimetric based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of MPG in human HeLa cell extracts at 50 to 300 uM using 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by ge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-3-methyladenine glycosylase 1(Escherichia coli (strain K12))TBA
LigandPNGBDBM50488841(3-METHYLADENINE | CHEBI:38635)
Affinity DataIC50:  1.50E+6nMAssay Description:Inhibition of Escherichia coli DNA-3-methyladenine glycosylase 1More data for this Ligand-Target Pair