TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenase in human cellMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Invitro inhibitory activity against polymorphonuclear leukocyte 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 2.53E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 4.16E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 7.03E+4nMAssay Description:Binding affinity to human 5-LOX using linoleic acid as substrateMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataKi: 1.40E+5nMAssay Description:Binding affinity to human 5-LOX-linoleic acid complexMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition by H2DCFDA staining-based fluor...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University
Curated by ChEMBL
Guru Nanak Dev University
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyteMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair