Affinity DataKi: 1.86nM ΔG°: -50.7kJ/mole IC50: 1.78E+3nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
Affinity DataKi: 2.17nM ΔG°: -50.3kJ/mole IC50: 2.07E+3nMT: 2°CAssay Description:Threefold dilution series of inhibitors in assay buffer were prepared in wells of a microtiter plate (final concentration stating from 2uM), and TAMR...More data for this Ligand-Target Pair
TargetAurora kinase A/Targeting protein for Xklp2(Homo sapiens (Human))
Nirma University
Curated by ChEMBL
Nirma University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of Aurora A/TPX2 (unknown origin) pre-incubated for 1 hr followed by FL-Kemptide substrate and ATP additionMore data for this Ligand-Target Pair
Affinity DataKd: 4.34nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair
Affinity DataKd: 0.527nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair
Affinity DataKd: 0.544nMT: 2°CAssay Description:A stock solution was prepared containing complex of Aurora A and Compound I (final total concentrations of 6nM and 5nM, respectively). Separately, se...More data for this Ligand-Target Pair