Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 7A1'
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  195nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)
Affinity DataIC50:  546nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of cytochrome P450 Cholesterol 7-alpha-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 7A1(Rattus norvegicus)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of lanosterol 14 alpha-demethylase cytochrome P450 51AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed